Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

[HTML][HTML] Bacteriophages of the human gut: the “known unknown” of the microbiome

AN Shkoporov, C Hill - Cell host & microbe, 2019 - cell.com
The human gut microbiome is a dense and taxonomically diverse consortium of
microorganisms. While the bacterial components of the microbiome have received …

[HTML][HTML] Advantages and limitations of bacteriophages for the treatment of bacterial infections

N Principi, E Silvestri, S Esposito - Frontiers in pharmacology, 2019 - frontiersin.org
Bacteriophages (BPs) are viruses that can infect and kill bacteria without any negative effect
on human or animal cells. For this reason, it is supposed that they can be used, alone or in …

Phage puppet masters of the marine microbial realm

M Breitbart, C Bonnain, K Malki, NA Sawaya - Nature microbiology, 2018 - nature.com
Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …

Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage

A Fluckiger, R Daillère, M Sassi, BS Sixt, P Liu, F Loos… - Science, 2020 - science.org
Intestinal microbiota have been proposed to induce commensal-specific memory T cells that
cross-react with tumor-associated antigens. We identified major histocompatibility complex …

Plankton networks driving carbon export in the oligotrophic ocean

L Guidi, S Chaffron, L Bittner, D Eveillard, A Larhlimi… - Nature, 2016 - nature.com
The biological carbon pump is the process by which CO2 is transformed to organic carbon
via photosynthesis, exported through sinking particles, and finally sequestered in the deep …

Revisiting the rules of life for viruses of microorganisms

AMS Correa, C Howard-Varona, SR Coy… - Nature Reviews …, 2021 - nature.com
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

[HTML][HTML] Biotechnological applications of bacteriophages: State of the art

LK Harada, EC Silva, WF Campos, FS Del Fiol… - Microbiological …, 2018 - Elsevier
Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …

[HTML][HTML] Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms

WN Chaudhry, J Concepcion-Acevedo, T Park… - PloS one, 2017 - journals.plos.org
In contrast to planktonic cells, bacteria imbedded biofilms are notoriously refractory to
treatment by antibiotics or bacteriophage (phage) used alone. Given that the mechanisms of …