Importance Congenital cytomegalovirus (cCMV) infection is the most common congenital
infection and the leading acquired cause of developmental disabilities and sensorineural …

Highlights•A normal microbiome shapes the immune system and promotes host
health.•Vaccine efficacy is altered by host, environmental, and viral factors.•The gut …

Vaccinating women in pregnancy (ie, maternal immunization) has emerged as a promising
tool to tackle infant morbidity and mortality worldwide. This approach nurtures a 'gift of …

Commencing lifelong antiretroviral therapy (ART) immediately following HIV diagnosis
(Option B+) has dramatically improved the health of HIV-infected women and their children …

While preventing vertical HIV transmission has been very successful, HIV-exposed
uninfected infants (iHEU) experience an elevated risk to infections compared to HIV …

In stark contrast to the rapid development of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), an effective human immunodeficiency virus (HIV) …

Viruses, when used as vectors for vaccine antigen delivery, can induce strong cellular and
humoral responses against target epitopes. Recent work by Hansen et al. describes the use …

Purpose This review article focuses on preventing vertical transmission of hepatitis B virus
(HBV) among pregnant women living in sub-Saharan Africa (SSA), where disease is …

Background Rotavirus vaccines reduce rotavirus-related deaths and hospitalisations but are
less effective in high child mortality countries. The human RV3-BB neonatal G3P [6] rotavirus …

Pertussis ('whooping cough') is a severe respiratory tract infection that primarily affects
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …