Role of Shankhpushpi (Convolvulus pluricaulis) in neurological disorders: An umbrella review covering evidence from ethnopharmacology to clinical studies

R Sharma, RK Singla, S Banerjee, B Sinha… - Neuroscience & …, 2022 - Elsevier
C. pluricaulis Choisy (C. pluricaulis), a perennial herb aka C. microphyllus Sieb. and C.
Prostratus Forsk. is being used as a traditional folk medicine for a variety of ailments. In this …

[HTML][HTML] Gut microbiota derived bile acid metabolites maintain the homeostasis of gut and systemic immunity

X Su, Y Gao, R Yang - Frontiers in Immunology, 2023 - frontiersin.org
Bile acids (BAs) as cholesterol-derived molecules play an essential role in some
physiological processes such as nutrient absorption, glucose homeostasis and regulation of …

Activation of SIRT1 alleviates ferroptosis in the early brain injury after subarachnoid hemorrhage

B Yuan, XD Zhao, JD Shen, SJ Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Ferroptosis is a regulated cell death that characterizes the lethal lipid peroxidation and iron
overload, which may contribute to early brain injury (EBI) pathogenesis after subarachnoid …

Emerging role of neuron‐glia in neurological disorders: at a glance

MM Rahman, MR Islam, M Yamin… - Oxidative medicine …, 2022 - Wiley Online Library
Based on the diverse physiological influence, the impact of glial cells has become much
more evident on neurological illnesses, resulting in the origins of many diseases appearing …

Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage

X Deng, Y Wu, Z Hu, S Wang, S Zhou, C Zhou… - Frontiers in …, 2023 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a cerebrovascular accident with an acute onset, severe
disease characteristics, and poor prognosis. Within 72 hours after the occurrence of SAH, a …

Mitochondria-targeted antioxidants, an innovative class of antioxidant compounds for neurodegenerative diseases: perspectives and limitations

M Fields, A Marcuzzi, A Gonelli, C Celeghini… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

New pathways identify novel drug targets for the prevention and treatment of Alzheimer's disease

B Penke, M Szűcs, F Bogár - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is an incurable, progressive neurodegenerative disorder. AD is a
complex and multifactorial disease that is responsible for 60–80% of dementia cases. Aging …

BACE1 Inhibitors for Alzheimer's Disease: The Past, Present and Any Future?

FH Bazzari, AH Bazzari - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and the most
common cause of dementia in the elderly. The complexity of AD has hindered the …

Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products

MM Rahman, MT Sarker, MA Alam Tumpa… - Frontiers in …, 2022 - frontiersin.org
Cancer is commonly thought to be the product of irregular cell division. According to the
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …