[HTML][HTML] Biologics for tendon repair

D Docheva, SA Müller, M Majewski… - Advanced drug delivery …, 2015 - Elsevier
Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

[HTML][HTML] Choosing the right cell line for acute myeloid leukemia (AML) research

R Skopek, M Palusińska, K Kaczor-Keller… - International journal of …, 2023 - mdpi.com
Immortalized cell lines are widely used in vitro tools in oncology and hematology research.
While these cell lines represent artificial systems and may accumulate genetic aberrations …

Development of a clay based bioink for 3D cell printing for skeletal application

T Ahlfeld, G Cidonio, D Kilian, S Duin… - …, 2017 - iopscience.iop.org
Three-dimensional printing of cell-laden hydrogels has evolved as a promising approach on
the route to patient-specific or complex tissue-engineered constructs. However, it is still …

Engineering considerations on extrusion-based bioprinting: interactions of material behavior, mechanical forces and cells in the printing needle

J Emmermacher, D Spura, J Cziommer, D Kilian… - …, 2020 - iopscience.iop.org
Systematic analysis of the extrusion process in 3D bioprinting is mandatory for process
optimization concerning production speed, shape fidelity of the 3D construct and cell …

[HTML][HTML] Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy

JC Estrada, Y Torres, A Benguria, A Dopazo… - Cell death & …, 2013 - nature.com
In most clinical trials, human mesenchymal stem cells (hMSCs) are expanded in vitro before
implantation. The genetic stability of human stem cells is critical for their clinical use …

A novel plasma-based bioink stimulates cell proliferation and differentiation in bioprinted, mineralized constructs

T Ahlfeld, N Cubo-Mateo, S Cometta… - … applied materials & …, 2020 - ACS Publications
Extrusion-based bioprinting, also known as 3D bioplotting, is a powerful tool for the
fabrication of tissue equivalents with spatially defined cell distribution. Even though …

Tissue engineering for bone defect healing: an update on a multi-component approach

I Drosse, E Volkmer, R Capanna, P De Biase… - Injury, 2008 - Elsevier
The need for an interdisciplinary approach in order to establish new therapeutic strategies
for the therapy of bone defects has been acknowledged by the scientific community for many …

Bioprinting of mineralized constructs utilizing multichannel plotting of a self-setting calcium phosphate cement and a cell-laden bioink

T Ahlfeld, F Doberenz, D Kilian, C Vater, P Korn… - …, 2018 - iopscience.iop.org
Due to their characteristic resemblance of the mineral component of bone, calcium
phosphates are widely accepted as optimal bone substitute materials. Recent research …

Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell …

F Haasters, WC Prall, D Anz, C Bourquin… - Journal of …, 2009 - Wiley Online Library
Human mesenchymal stem cells (hMSC) are a heterogeneous cell population, which is
reflected in varying morphological and biological properties. Three subpopulations with …

[HTML][HTML] Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I

C Popov, T Radic, F Haasters, WC Prall, A Aszodi… - Cell death & …, 2011 - nature.com
Although mesenchymal stem cells (MSCs) are the natural source for bone regeneration, the
exact mechanisms governing MSC crosstalk with collagen I have not yet been uncovered …