Despite centuries since the discovery and study of cancer, cancer is still a lethal and
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …

Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …

Cancer is a complex disease resulting from abnormal cell growth that is induced by a
number of genetic and environmental factors. The tumor microenvironment (TME), which …

Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …

Cancer-associated fibroblasts (CAFs) are abundant and important components of the
tumour mesenchyme, and have been extensively studied for their role in primary tumours …

Lymph node metastasis (LNM) is the prominent route of gastric cancer dissemination, and
usually leads to tumor progression and a dismal prognosis of gastric cancer. Although …

Cadmium (Cd) is a heavy metal that has been widely reported to be linked to the onset and
progression of breast cancer (BC). However, the mechanism of Cd-induced mammary …

The mechanisms underlying the involvement of long non-coding RNAs (lncRNAs) in the
metastasis of small cell lung cancer (SCLC) remain largely unknown. Here, we identified …

Tumours are complex systems with dynamic interactions between tumour cells, non-tumour
cells, and extracellular components that comprise the tumour microenvironment (TME). The …

Cisplatin (CPT) is one of the standard treatments for hepatocellular carcinoma (HCC).
However, its use is limits as a monotherapy due to drug resistance, and the underlying …