Engineered nanomaterials: The challenges and opportunities for nanomedicines

F Albalawi, MZ Hussein, S Fakurazi… - International journal of …, 2021 - Taylor & Francis
The emergence of nanotechnology as a key enabling technology over the past years has
opened avenues for new and innovative applications in nanomedicine. From the business …

Role of artificial intelligence and machine learning in nanosafety

DA Winkler - Small, 2020 - Wiley Online Library
Robotics and automation provide potentially paradigm shifting improvements in the way
materials are synthesized and characterized, generating large, complex data sets that are …

[HTML][HTML] Using Machine Learning to make nanomaterials sustainable

JJ Scott-Fordsmand, MJB Amorim - Science of The Total Environment, 2023 - Elsevier
Sustainable development is a key challenge for contemporary human societies; failure to
achieve sustainability could threaten human survival. In this review article, we illustrate how …

[HTML][HTML] High throughput data-based, toxicity pathway-oriented development of a quantitative adverse outcome pathway network linking AHR activation to lung …

Y Jin, G Qi, Y Shou, D Li, Y Liu, H Guan… - Journal of Hazardous …, 2022 - Elsevier
The quantitative adverse outcome pathway (qAOP) is proposed to inform dose-responses at
multiple biological levels for the purpose of toxicity prediction. So far, qAOP models …

Daphnia magna and mixture toxicity with nanomaterials–Current status and perspectives in data-driven risk prediction

DST Martinez, LJA Ellis, GH Da Silva, R Petry… - Nano Today, 2022 - Elsevier
The aquatic ecosystem is the final destination of most industrial residues and agrochemicals
resulting in organisms being exposed to a complex mixture of contaminants. Nanomaterials …

Biomarkers of nanomaterials hazard from multi-layer data

V Fortino, PAS Kinaret, M Fratello, A Serra… - Nature …, 2022 - nature.com
There is an urgent need to apply effective, data-driven approaches to reliably predict
engineered nanomaterial (ENM) toxicity. Here we introduce a predictive computational …

Digital innovation enabled nanomaterial manufacturing; machine learning strategies and green perspectives

G Konstantopoulos, EP Koumoulos, CA Charitidis - Nanomaterials, 2022 - mdpi.com
Machine learning has been an emerging scientific field serving the modern multidisciplinary
needs in the Materials Science and Manufacturing sector. The taxonomy and mapping of …

Toxicogenomics Data for Chemical Safety Assessment and Development of New Approach Methodologies: An Adverse Outcome Pathway‐Based Approach

LA Saarimäki, J Morikka, A Pavel… - Advanced …, 2023 - Wiley Online Library
Mechanistic toxicology provides a powerful approach to inform on the safety of chemicals
and the development of safe‐by‐design compounds. Although toxicogenomics supports …

Rise of deep learning clinical applications and challenges in omics data: a systematic review

MA Mohammed, KH Abdulkareem, AM Dinar… - Diagnostics, 2023 - mdpi.com
This research aims to review and evaluate the most relevant scientific studies about deep
learning (DL) models in the omics field. It also aims to realize the potential of DL techniques …

[HTML][HTML] Systems toxicology to advance human and environmental hazard assessment: A roadmap for advanced materials

MJB Amorim, W Peijnenburg, D Greco, LA Saarimäki… - Nano Today, 2023 - Elsevier
Abstract Ideally, a Systems Toxicology (ST) approach is aimed at by (eco) toxicologists, ie a
multidisciplinary area incorporating classical toxicological concepts with omics technologies …