The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …

The blood–brain barrier (BBB) protects the central nervous system (CNS) from unregulated
exposure to the blood and its contents. The BBB also controls the blood-to-brain and brain …

Ischemic stroke is a main cause of cognitive neurological deficits and disability worldwide
due to a plethora of neuronal apoptosis. Unfortunately, numerous neuroprotectants for …

The way sporadic Parkinson's disease (PD) is perceived has undergone drastic changes in
recent decades. For a long time, PD was considered a brain disease characterized by motor …

CRISPR genome editing can potentially treat the root causes of many genetic diseases,
including central nervous system (CNS) disorders. However, the promise of brain‐targeted …

With an aging population that has been increasing in recent years, the need for the
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …

The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …

The discovery of effective drugs for the treatment of neurodegenerative disorders (NDs) is a
deadlock. Due to their complex etiology and high heterogeneity, progresses in the …

The brain is one of the most energy-consuming organs in the body. Satisfying such energy
demand requires compartmentalized, cell-specific metabolic processes, known to be …

Neuroimaging-driven brain age estimation has introduced a robust (reliable and heritable)
biomarker for detecting and monitoring neurodegenerative diseases. Here, we computed …