[HTML][HTML] Genome-wide classification of epigenetic activity reveals regions of enriched heritability in immune-related traits

M Stricker, W Zhang, WY Cheng, S Gazal, C Dendrou… - Cell genomics, 2024 - cell.com
Epigenetics underpins the regulation of genes known to play a key role in the adaptive and
innate immune system (AIIS). We developed a method, EpiNN, that leverages epigenetic …

Epigenetic control of metabolic identity across cell types

MP Pacheco, D Gerard, RJ Mangan, AR Chapman… - bioRxiv, 2024 - biorxiv.org
Constraint-based network modelling is a powerful tool for analysing cellular metabolism at
genomic scale. Here, we conducted an integrative analysis of metabolic networks …