Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …

Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

G protein-coupled receptors (GPCRs) belong to a superfamily of cell surface signalling
proteins that have a pivotal role in many physiological functions and in multiple diseases …

ETHNOPHARMACOLOGICAL RELEVANCE: Coptidis Rhizoma (Huanglian) and its major
component, berberine, have drawn extensive attention toward their antineoplastic effects in …

There is growing evidence for a connection between inflammation and tumor development,
and the nuclear factor kappa B (NF-κB), a proinflammatory transcription factor, is …

Sesquiterpene lactones are a large group of secondary plant metabolites mostly known from
the Asteraceae family. They exert a broad variety of different biological activities. This review …

Nuclear factor-kappa B (NF-κB) is a transcription factor that plays a critical role across many
cellular processes including embryonic and neuronal development, cell proliferation …

Background As a natural compound extracted from a variety of hot peppers, capsaicin has
drawn increasing attention to its anti-cancer effects against multiple human cancers …

Prostate cancer (PCa) is by far the most commonly diagnosed cancer in men worldwide.
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …

It has become increasingly clear that deregulation of the NF κ B signaling cascade is a
common underlying feature of many human ailments including cancers. The past two …