RAGE Isoforms, its Ligands and their Role in Pathophysiology of Alzheimer's Disease

RC Chellappa, R Palanisamy… - Current Alzheimer …, 2020 - ingentaconnect.com
Receptor for Advanced Glycation End product (RAGE) plays a crucial role in a variety of
physiological and pathological processes due to its ability to bind a broad repertory of …

[HTML][HTML] An open-label, single-arm pilot study of tocotrienols supplementation on improving memory and attention in healthy young adults

RYX Par, CWL Teo, JJK Tan, YW Ung, KS Heng… - Journal of functional …, 2022 - Elsevier
This study aimed to investigate the beneficial effects of tocotrienols (T3) supplementation on
one's attention and memory. Eleven healthy subjects were enrolled to receive placebo …

Sex as a Determinant of Age-Related Changes in the Brain

DE Burmistrov, SV Gudkov, C Franceschi… - International Journal of …, 2024 - mdpi.com
The notion of notable anatomical, biochemical, and behavioral distinctions within male and
female brains has been a contentious topic of interest within the scientific community over …

Oxidative Stress and Neurodegeneration: Insights and Therapeutic Strategies for Parkinson's Disease

E Bej, P Cesare, AR Volpe, M d'Angelo… - Neurology …, 2024 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative condition marked by the
gradual deterioration of dopaminergic neurons in the substantia nigra. Oxidative stress has …

[HTML][HTML] GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

HH Park, HS Kwon, KY Lee, YE Kim, JW Son… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
GV1001, which mimics the activity of human telomerase reverse transcriptase, protects
neural cells from amyloid beta (Aβ) toxicity and other stressors through extra-telomeric …

Accelerated neuronal aging in vitro ∼melting watch ∼

E Inagaki, S Yoshimatsu, H Okano - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
In developed countries, the aging of the population and the associated increase in age-
related diseases are causing major unresolved medical, social, and environmental matters …

Small effects of olfactory identification and discrimination on global cognitive and executive performance over 1 year in aging people without a history of age-related …

LM Nováková, H Georgi, K Vlčková, M Kopeček… - Physiology & …, 2024 - Elsevier
Olfactory and cognitive performance share neural correlates profoundly affected by
physiological aging. However, whether odor identification and discrimination scores predict …

MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model

SS Deepa, N Thadathil, J Corral, S Mohammed… - Cell Calcium, 2024 - Elsevier
The necroptotic effector molecule MLKL accumulates in neurons over the lifespan of mice,
and its downregulation has the potential to improve cognition through neuroinflammation …

Bioaccumulation and Tolerance Indices of Cadmium in Wheat Plants Grown in Cadmium-Spiked Soil: Health Risk Assessment

MA Halim, MM Rahman, D Mondal… - Frontiers in …, 2021 - frontiersin.org
Farmers use wastewater for irrigation in many developing countries, for example
Bangladesh, India, China, Sri Lanka and Vietnam because they have limited access to clean …

Neutrophil-Mediated Progression of Mild Cognitive Impairment to Dementia

KJ Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment is a serious condition that begins with amnesia and progresses to
cognitive decline, behavioral dysfunction, and neuropsychiatric impairment. In the final …