Taurine and oxidative stress in retinal health and disease

V Castelli, A Paladini, M d'Angelo… - CNS neuroscience & …, 2021 - Wiley Online Library
Retinal disorders are leading causes of blindness and are due to an imbalance between
reactive oxygen species and antioxidant scavenger (in favor of pro‐oxidant species) or a …

Glia: a major player in glutamate–GABA dysregulation‐mediated neurodegeneration

A Sood, K Preeti, V Fernandes… - Journal of …, 2021 - Wiley Online Library
The imbalance between glutamate and γ‐aminobutyric acid (GABA) results in the loss of
synaptic strength leading to neurodegeneration. The dogma on the field considered neurons …

Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

C Cai, SA Zambach, S Grubb, L Tao, C He, BL Lind… - Nature aging, 2023 - nature.com
The microvascular inflow tract, comprising the penetrating arterioles, precapillary sphincters
and first-order capillaries, is the bottleneck for brain blood flow and energy supply. Exactly …

Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies

Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …

Insights into the effects of mesenchymal stem cell-derived secretome in Parkinson's disease

M d'Angelo, A Cimini, V Castelli - International Journal of Molecular …, 2020 - mdpi.com
Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …

Seaweed sulfated polysaccharides and their medicinal properties

OO Zaitseva, MI Sergushkina, AN Khudyakov… - Algal Research, 2022 - Elsevier
Currently, biologically active natural products become more and more popular among
consumers, both in the form of food supplements and cosmetic products, and as medicines …

[PDF][PDF] Protective effects of pioglitazone on cognitive impairment and the underlying mechanisms: a review of literature

A Alhowail, R Alsikhan, M Alsaud… - Drug Design …, 2022 - Taylor & Francis
Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, is
known to have anti-inflammatory and anti-oxidant effects on the brain, and its clinical …

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach

M Ebrahimi, P Norouzi, H Aazami… - International journal of …, 2021 - Elsevier
COVID-19 disease has put life of people in stress worldwide from many aspects. Since the
virus has mutated in absolutely short period of time the challenge to find a suitable vaccine …

Metabolic regulation of glia and their neuroinflammatory role in Alzheimer's disease

K Preeti, A Sood, V Fernandes - Cellular and Molecular Neurobiology, 2022 - Springer
Alzheimer's disease (AD) is an aging-related neurodegenerative disorder. It is characterized
clinically by progressive memory loss and impaired cognitive function. Its progression occurs …

Role of sirtuins in modulating neurodegeneration of the enteric nervous system and central nervous system

P Chandramowlishwaran, A Vijay, D Abraham… - Frontiers in …, 2020 - frontiersin.org
Neurodegeneration of the central and enteric nervous systems is a common feature of aging
and aging-related diseases, and is accelerated in individuals with metabolic dysfunction …