Due to globalization and sophisticated western and sedentary lifestyle, metabolic syndrome
has emerged as a serious public health challenge. Obesity is significantly increasing …

The natriuretic peptide family (NPs) is a group of natural endocrine hormones, containing a
17-amino acid ring structure connected by disulfide bonds of two cysteines. In this review …

Atrial natriuretic peptide (ANP), encoded by Nppa, is a vasodilatory hormone that promotes
salt excretion. Genome-wide association studies identified Nppa as a causative factor of …

Dysregulated inflammasome activation and interleukin (IL)-1β production are associated
with several inflammatory disorders. Three different routes can lead to inflammasome …

Inflammation, by inducing a tumor-promoting microenvironment, is a hallmark for prostate
cancer (PCa) progression. NOD-like receptor protein 3 (NLRP3)-inflammasome activation …

The nuclear factor-kappa B (NF-κB) pathway is an evolutionarily conserved signaling
pathway that plays a central role in immune responses and inflammation. Here, we show …

Abstract N-terminal-pro-B-type-natriuretic peptide (NT-proBNP) was a predictive marker of
cardiovascular disease (CVD)-related death in chronic dialysis patients. NT-proBNP was …

Diuretics and renin-angiotensin system blockers are often insufficient to control the blood
pressure (BP) in salt-sensitive (SS) subjects. Abundant data support the proposal that the …

Cardiac natriuretic peptides have long been known to act as main players in the homeostatic
control of blood pressure, salt and water balance. However, in the last few decades, new …

Cardiorenal syndrome (CRS) results from complex interaction between heart and kidneys,
inducing simultaneous acute or chronic dysfunction of these organs. Although its incidence …