Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

Biothermodynamics of viruses from absolute zero (1950) to virothermodynamics (2022)

M Popovic - Vaccines, 2022 - mdpi.com
Biothermodynamics of viruses is among the youngest but most rapidly developing scientific
disciplines. During the COVID-19 pandemic, it closely followed the results published by …

Phage–Antibiotic therapy as a promising strategy to combat multidrug-resistant infections and to enhance antimicrobial efficiency

C Liu, Q Hong, RYK Chang, PCL Kwok, HK Chan - Antibiotics, 2022 - mdpi.com
Infections caused by multidrug-resistant (MDR) bacteria have highlighted the importance of
the development of new antimicrobial agents. While bacteriophages (phages) are widely …

The SARS-CoV-2 Hydra, a tiny monster from the 21st century: Thermodynamics of the BA. 5.2 and BF. 7 variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 resembles the ancient mythical creature Hydra. Just like with the Hydra, when
one head is cut, it is followed by appearance of two more heads, suppression of one SARS …

Exploiting phage-antibiotic synergies to disrupt Pseudomonas aeruginosa PAO1 biofilms in the context of orthopedic infections

S De Soir, H Parée, NHN Kamarudin… - Microbiology …, 2024 - Am Soc Microbiol
In recent years, bacteriophages (or phages) have reentered the spotlight as alternative or
adjuvant therapeutic agents to antibiotics. Their efficacy in more recalcitrant forms of …

[HTML][HTML] Bacteriophage therapy and current delivery strategies for orthopedic infections: A SCOPING review

J Young, SW Lee, MJ Shariyate, A Cronin, JJ Wixted… - Journal of Infection, 2024 - Elsevier
Objectives Interest in phages as adjunctive therapy to treat difficult infections has grown in
the last decade. However, phage dosing and delivery for orthopedic infections have not …

“Two is better than one”: The multifactorial nature of phage-antibiotic combinatorial treatments against ESKAPE-induced infections

GBN Fungo, JCW Uy, KLJ Porciuncula… - Phage, 2023 - liebertpub.com
Phage-antibiotic synergy (PAS) has been extensively explored over the past decade, with
the aim of developing more effective treatments against multidrug-resistant organisms …

Synergy of a virulent phage (φAB182) with antibiotics leading to successful elimination of biofilms formed by MDR Acinetobacter baumannii

M Vashisth, S Yashveer, AB Jaglan… - Canadian Journal of …, 2022 - cdnsciencepub.com
Emergence of multiple drug resistant (MDR) strains of Acinetobacter baumannii and a
withering drug discovery pipeline necessitates the search for effective alternatives to replace …

The strategy of biopreservation of meat product against MRSA using lytic domain of lysin from Staphylococcus aureus bacteriophage

J Yan, R Yang, S Yu, W Zhao - Food Bioscience, 2021 - Elsevier
Staphylococcus aureus is a notorious foodborne pathogen capable of producing various
toxins including heat-stable enterotoxin, forming biofilm, evolving to multidrug-resistant …

Development of effective antibacterial treatment: lessons from the past and novel approaches

M Di Luca, T Marzo - Antibiotics, 2021 - mdpi.com
In the last three decades, the appearance and rapid diffusion of antibiotic-resistant bacterial
strains have been observed. Contextually, the discovery rate of novel antibacterial agents …