Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

A critical review on human malaria and schistosomiasis vaccines: current state, recent advancements, and developments

AJ Siddiqui, J Bhardwaj, J Saxena, S Jahan, M Snoussi… - Vaccines, 2023 - mdpi.com
Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …

Immunosuppression in Malaria: Do Plasmodium falciparum Parasites Hijack the Host?

CL Calle, B Mordmüller, A Singh - Pathogens, 2021 - mdpi.com
Malaria reflects not only a state of immune activation, but also a state of general immune
defect or immunosuppression, of complex etiology that can last longer than the actual …

Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

IN Waghela, KL Mallory, JA Taylor… - Frontiers in …, 2022 - frontiersin.org
The secreted malarial protein, Cell-Traversal protein for Ookinetes and Sporozoites
(CelTOS), is highly conserved among Plasmodium species, and plays a role in the invasion …

An optimal control model to understand the potential impact of the new vaccine and transmission-blocking drugs for malaria: A case study in papua and west papua …

BD Handari, RA Ramadhani, CW Chukwu… - Vaccines, 2022 - mdpi.com
Malaria is one of the major causes of a high death rate due to infectious diseases every
year. Despite attempts to eradicate the disease, results have not been very successful. New …

[图书][B] Parasitology: a conceptual approach

ES Loker, BV Hofkin - 2022 - taylorfrancis.com
Produced amidst the still rippling effects of a pandemic and as the world experiences the
increasing burden of global warming and a rapidly changing biosphere, the second edition …

A multi-epitope vaccine designed against blood-stage of malaria: An immunoinformatic and structural approach

A Atapour, P Vosough, S Jafari, GA Sarab - Scientific Reports, 2022 - nature.com
Malaria is a complex disease caused by parasites of the genus Plasmodium and is the
leading cause of morbidity and mortality worldwide. The most severe form of malaria …

First-in-human randomised trial and follow-up study of Plasmodium falciparum blood-stage malaria vaccine BK-SE36 with CpG-ODN (K3)

S Ezoe, NMQ Palacpac, K Tetsutani, K Yamamoto… - Vaccine, 2020 - Elsevier
Background BK-SE36 is blood-stage malaria vaccine candidate that is undergoing clinical
trials. Here, the safety and immunogenicity of BK-SE36 with a novel adjuvant, CpG-ODN …

[HTML][HTML] Malaria vaccines: facing unknowns

NMQ Palacpac, T Horii - F1000Research, 2020 - ncbi.nlm.nih.gov
Much of the gain in malaria control, in terms of regional achievements in restricting
geographical spread and reducing malaria cases and deaths, can be attributed to large …

A review on RNA interference studies in Anophelines to reveal candidate genes for malaria transmission blocking vaccine

M Yadav, N Dahiya, S Janjoter, D Kataria, R Dixit… - Life Sciences, 2024 - Elsevier
Malaria is a major public health concern. The development of parasite-based vaccine
RTS/AS01 has some therapeutic value but its lower efficacy is one of the major limitations …