[HTML][HTML] Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …
[HTML][HTML] Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states
LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …
[HTML][HTML] Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace
Tissues are highly complicated with spatial heterogeneity in gene expression. However, the
cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual …
cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual …
[HTML][HTML] NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 …
I Tsukalov, I Sánchez-Cerrillo, O Rajas… - Nature …, 2024 - nature.com
Increased recruitment of transitional and non-classical monocytes in the lung during SARS-
CoV-2 infection is associated with COVID-19 severity. However, whether specific innate …
CoV-2 infection is associated with COVID-19 severity. However, whether specific innate …
[HTML][HTML] Developmental Impacts of Epigenetics and Metabolism in COVID-19
Developmental biology is intricately regulated by epigenetics and metabolism but the
mechanisms are not completely understood. The situation becomes even more complicated …
mechanisms are not completely understood. The situation becomes even more complicated …
Cognitive concerns are a risk factor for mortality in people with HIV and coronavirus disease 2019
Background: Data supporting dementia as a risk factor for coronavirus disease 2019 (COVID-
19) mortality relied on ICD-10 codes, yet nearly 40% of individuals with probable dementia …
19) mortality relied on ICD-10 codes, yet nearly 40% of individuals with probable dementia …
Differential host responses within the upper respiratory tract and peripheral blood of children and adults with SARS-CoV-2 infection
Age is among the strongest risk factors for severe outcomes from SARS-CoV-2 infection. We
sought to evaluate associations between age and both mucosal and systemic host …
sought to evaluate associations between age and both mucosal and systemic host …
Single-cell RNA analysis of chemokine expression in heterogeneous CD14+ monocytes with lipopolysaccharide-induced bone resorption
J Luo, J Lu, J Zeng, Y Ma, Q Gong, Z Wang… - Experimental Cell …, 2022 - Elsevier
Lipopolysaccharide (LPS)-induced bone resorption has normally been found in
inflammatory bone diseases, but the underlying mechanism is currently unclear. Since LPS …
inflammatory bone diseases, but the underlying mechanism is currently unclear. Since LPS …
[PDF][PDF] Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States. Cells 2022, 11, 847
LF Schimke, AHC Marques, GC Baiocchi… - 2022 - observatorio.fm.usp.br
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …
[引用][C] COVID-19: A Retrospective Study and The Relationship Between Myeloid Cells and The Disease Severity
K Alashie, D Almuaili