Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

The number of patients with type 2 diabetes mellitus (T2DM), which is mainly characterized
by insulin resistance and insulin secretion deficiency, has been soaring in recent years …

Bisphenols and phthalates, chemicals frequently used in plastic products, promote obesity in
cell and animal models. However, these well-known metabolism-disrupting chemicals …

Triphenyl phosphate (TPP) is a frequently used aryl organophosphate flame retardant.
Epidemiological studies have shown that TPP and its metabolite diphenyl phosphate (DPP) …

Triphenyl phosphate (TPHP) has been widely used as flame retardants and been detected
with increasing frequency in environment. TPHP can transform into mono-hydroxylated …

Although the prevalence of heart failure with preserved ejection fraction (HFpEF) is
increasing, evidence-based therapies for HFpEF remain limited, likely due to an incomplete …

The emerging endocrine disruption chemicals organophosphate esters (OPEs) pose high
risk of metabolic disruption. However, limited information is available on physiological …

Abstract 3T3-L1 pre-adipocytes are used commonly to identify new adipogens, but this cell
line has been shown to produce variable results. Here, potential adipogenic chemicals …

Abstract Identification of Endocrine-Disrupting Chemicals (EDCs) in a regulatory context
requires a high level of evidence. However, lines of evidence (eg human, in vivo, in vitro or …

Triphenyl phosphate (TPhP) is an organophosphate flame retardant that is widely used in
many commercial products. The United States Environmental Protection Agency has listed …