The patterns of small bowel motility: physiology and implications in organic disease and functional disorders

HUSEBYE - Neurogastroenterology & Motility, 1999 - Wiley Online Library
The physiology and pathophysiology of small bowel motility are reviewed with particular
focus on the motility patterns and periods that are detected by intraluminal manometry …

The effects of mechanical forces on intestinal physiology and pathology

CP Gayer, MD Basson - Cellular signalling, 2009 - Elsevier
The epithelial and non-epithelial cells of the intestinal wall experience a myriad of physical
forces including strain, shear, and villous motility during normal gut function. Pathologic …

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs

B Hens, Y Tsume, M Bermejo, P Paixao… - Molecular …, 2017 - ACS Publications
In this study, we determined the pH and buffer capacity of human gastrointestinal (GI) fluids
(aspirated from the stomach, duodenum, proximal jejunum, and mid/distal jejunum) as a …

Exploring gastrointestinal variables affecting drug and formulation behavior: methodologies, challenges and opportunities

B Hens, M Corsetti, R Spiller, L Marciani… - International Journal of …, 2017 - Elsevier
Various gastrointestinal (GI) factors affect drug and formulation behavior after oral
administration, including GI transfer, motility, pH and GI fluid volume and composition. An in …

Physiology and pathophysiology of colonic motor activity: Part one of two

SK Sarna - Digestive diseases and sciences, 1991 - Springer
Major functions of the colon are to (1) absorb water, certain electrolytes, short chain fatty
acids, and bacterial metabolites;(2) slowly propel its luminal contents in the caudad …

[PDF][PDF] Abnormalities in proximal small bowel motility in patients with cirrhosis

J Chesta, C Defilippi, C Defilippi - Hepatology, 1993 - Wiley Online Library
Because altered intestinal motility could be involved in the pathogenesis of small intestine
bacterial overgrowth observed in some patients with cirrhosis, we investigated fasting …

Risk factors for prolonged postoperative ileus in colorectal surgery: a systematic review and meta-analysis

AC Quiroga-Centeno, KA Jerez-Torra… - World journal of …, 2020 - Springer
Background Prolonged postoperative ileus (PPOI) represents a frequent complication
following colorectal surgery, affecting approximately 10–15% of these patients. The …

[HTML][HTML] Diversity of the microbiota communities found in the various regions of the intestinal tract in healthy individuals and inflammatory bowel diseases

SA Lawal, A Voisin, H Olof… - Frontiers in …, 2023 - frontiersin.org
The severe and chronic inflammatory bowel diseases (IBD), Crohn disease and ulcerative
colitis, are characterized by persistent inflammation and gut damage. There is an increasing …

Generation of slow waves in membrane potential is an intrinsic property of interstitial cells of Cajal

JCF Lee, L Thuneberg, I Berezin… - American Journal of …, 1999 - journals.physiology.org
To reveal the unique intrinsic properties of interstitial cells of Cajal (ICC), morphological and
electrophysiological characteristics of isolated ICC from the adult mouse small intestine …

Update on gastrointestinal scintigraphy

AH Maurer, HP Parkman - Seminars in nuclear medicine, 2006 - Elsevier
Nuclear medicine offers a variety of studies for evaluating motility throughout the
gastrointestinal tract. Gastric emptying remains the “gold standard” for studying gastric motor …