Highly prevalent conditions with multiple and complex underlying etiologies are a challenge
to public health. Undernutrition, for example, affects 20% of children in the developing world …

The burgeoning interest in the field of epigenetics has precipitated the need to develop
approaches to strengthen causal inference when considering the role of epigenetic …

Today we can generate hundreds of gigabases of DNA and RNA sequencing data in a week
for less than US $5,000. The astonishing rate of data generation by these low-cost, high …

Common human diseases result from the interplay of many genes and environmental
factors. Therefore, a more integrative biology approach is needed to unravel the complexity …

Analyzing metabolites (small molecules< 1 kDa) in body fluids such as urine and plasma
using various spectroscopic methods provides information on the metabotype (metabolic …

Variation in gene expression is an important mechanism underlying susceptibility to
complex disease. The simultaneous genome-wide assay of gene expression and genetic …

Chronic adult periodontitis is a bacterially induced chronic inflammatory disease that
destroys the connective tissue and bone that support teeth. Concepts of the specific …

The molecular biology revolution led to an intense focus on the study of interactions
between DNA, RNA and protein biosynthesis in order to develop a more comprehensive …

The balanced weighting scheme of tree lasso and additional experimental results. We prove
that the weighting scheme of the tree-lasso penalty achieves a balanced penalization of all …

The enormous complexity of the human brain ultimately derives from a finite set of molecular
instructions encoded in the human genome. These instructions can be directly studied by …