Background The coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While …

Severe cases of COVID-19 are characterized by hyperinflammation induced by cytokine
storm, ARDS leading to multiorgan failure and death. JAK-STAT signaling has been …

Despite tremendous global efforts since the beginning of the COVID-19 pandemic, still only
a limited number of prophylactic and therapeutic options are available. Although vaccination …

Metabolic reprogramming is a common hallmark of cancer cells. Cancer cells exhibit
metabolic flexibility to maintain high proliferation and survival rates. In other words …

Gas6 (growth arrest-specific gene 6) is a widely expressed vitamin K-dependent protein that
is involved in many biological processes such as homeostatic regulation, inflammation and …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infected over 688
million people worldwide, causing public health concern and approximately 6.8 million …

Background Biomedical relation extraction (RE) is of great importance for researchers to
conduct systematic biomedical studies. It not only helps knowledge mining, such as …

Despite the great technological and medical advances in fighting viral diseases, new
therapies for most of them are still lacking, and existing antivirals suffer from major limitations …

Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances
and a major pollutant in households and ecosystems. In vertebrates, it was shown to affect …

The present disclosure relates to p38α mitogen-activated protein kinase inhibitors,
pharmaceutical compositions thereof, and the use of the p38α mitogen-activated protein …