Impact of comorbid affective disorders on longitudinal clinical outcomes in individuals at ultra-high risk for psychosis

F Schirmbeck, NC van Der Burg… - Schizophrenia …, 2022 - academic.oup.com
Introduction Diagnoses of anxiety and/or depression are common in subjects at Ultra-High
Risk for Psychosis (UHR) and associated with extensive functional impairment. Less is …

Expanding the search for emerging mental ill health to safeguard student potential and vocational success in high school: A narrative review

S Bowman, C McKinstry, L Howie… - Early Intervention in …, 2020 - Wiley Online Library
Aim Young people experiencing mental ill health are more likely than their healthy aged
peers to drop out of high school. This can result in social exclusion and vocational …

Negative symptoms mediate the relationship between neurocognition and function in individuals at ultrahigh risk for psychosis

LB Glenthøj, JRM Jepsen, C Hjorthøj… - Acta Psychiatrica …, 2017 - Wiley Online Library
Objective Neurocognition is known to impact functioning in individuals at ultrahigh risk
(UHR) for psychosis, but studies investigating potential mediators of this relationship are …

[HTML][HTML] Transdiagnostic dimensions of psychiatric comorbidity in individuals at clinical high risk for psychosis: a preliminary study informed by HiTOP

HR Cowan, VA Mittal - Frontiers in Psychiatry, 2021 - frontiersin.org
Background: Although psychiatric comorbidity is the norm among individuals at clinical high
risk for psychotic disorders (CHR), research has yet to examine transdiagnostic dimensional …

Distress related to psychotic symptoms in individuals at high risk of psychosis

RS Wilson, N Shryane, AR Yung, AP Morrison - Schizophrenia research, 2020 - Elsevier
This study assessed the relationship between distress, severity and frequency of attenuated
psychotic symptoms in individuals meeting Ultra High Risk (UHR) criteria, both at baseline …

Cerebral glutamate and gamma-aminobutyric acid levels in individuals at ultra-high risk for psychosis and the association with clinical symptoms and cognition

C Wenneberg, M Nordentoft, E Rostrup… - Biological Psychiatry …, 2020 - Elsevier
Background Studies examining glutamate or gamma-aminobutyric acid (GABA) in ultra-high
risk for psychosis (UHR) and the association with pathophysiology and cognition have …

[HTML][HTML] Characterizing psychosis risk traits in Africa: a longitudinal study of Kenyan adolescents

D Mamah, A Musau, VN Mutiso, A Owoso… - Schizophrenia …, 2016 - Elsevier
The schizophrenia prodrome has not been extensively studied in Africa. Identification of
prodromal behavioral symptoms holds promise for early intervention and prevention of …

Prediction of clinical outcomes beyond psychosis in the ultra‐high risk for psychosis population

A Polari, HP Yuen, P Amminger… - Early intervention in …, 2021 - Wiley Online Library
Aim Several prediction models have been introduced to identify young people at greatest
risk of transitioning to psychosis. To date, none has examined the possibility of developing a …

[HTML][HTML] Psychosocial factors associated with the risk of developing psychosis in a Mexican general population sample

T Domínguez-Martínez, T Sheinbaum, A Fresán… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence has linked an array of sociodemographic and psychosocial
factors with an increased risk of developing psychosis. However, research in samples from …

Brief rapport: Perceptual aberration in patients at ultra‐high risk for psychosis

L Clemmensen, TD Kristensen… - Early Intervention in …, 2024 - Wiley Online Library
Background Ultra‐high risk (UHR) is considered a forerunner of psychosis, but most UHR
individuals do not later convert, yet remain symptomatic, disabled and help‐seeking. Thus …