Secretin is secreted by S cells in the small intestine and affects the function of a number of
organ systems. Secretin receptors (SR) are expressed in the basolateral domain of several …

Secretin is the first hormone that has been discovered, inaugurating the era and the field of
endocrinology. Despite the initial focus, the interest in its actions faded away over the …

Body fluid homeostasis is critical for the survival of living organisms and hence is tightly
controlled. From initial studies on the effects of secretin (SCT) on renal water reabsorption in …

Secretin holds a unique place in the history of endocrinology and gastrointestinal
physiology, as it is the first peptide designated as a hormone. During the last century since …

Secretin is a key hormone of the intestinal phase of digestion which activates pancreatic,
bile duct and Brunner gland HCO3− secretion. Recently, the secretin receptor (SCTR) was …

The discovery of secretin initiated the field of endocrinology. Over the past century, multiple
gastrointestinal functions of secretin have been extensively studied, and it was discovered …

Secretin, a 27-amino acid gastrointestinal peptide, was initially discovered based on its
activities in stimulating pancreatic juice. In the past 20 years, secretin was demonstrated to …

Objective: Several gastrointestinal peptides are now recognized to have target functions
beyond the intestinal wall, including effects on adipocytes. Secretin (SEC), one of the first …

More than 1 billion people globally are suffering from hypertension, which is a long-term
incurable medical condition that can further lead to dangerous complications and death if left …

Secretin receptor (SCTR), the G-protein coupled receptor (GPCR) for secretin, has been
observed to be upregulated in a few tumor types while downregulated in others, promoting …