[HTML][HTML] The role of ai in drug discovery: challenges, opportunities, and strategies
A Blanco-Gonzalez, A Cabezon, A Seco-Gonzalez… - Pharmaceuticals, 2023 - mdpi.com
Artificial intelligence (AI) has the potential to revolutionize the drug discovery process,
offering improved efficiency, accuracy, and speed. However, the successful application of AI …
offering improved efficiency, accuracy, and speed. However, the successful application of AI …
Computational protein design for COVID-19 research and emerging therapeutics
As the world struggles with the ongoing COVID-19 pandemic, unprecedented obstacles
have continuously been traversed as new SARS-CoV-2 variants continually emerge …
have continuously been traversed as new SARS-CoV-2 variants continually emerge …
[HTML][HTML] Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD …
The new coronavirus SARS-COV-2, which emerged in late 2019 from Wuhan city of China
was regarded as causing agent of the COVID-19 pandemic. The primary protease which is …
was regarded as causing agent of the COVID-19 pandemic. The primary protease which is …
[HTML][HTML] Computer-assisted design of peptide-based radiotracers
In medical imaging, techniques such as magnetic resonance imaging, contrast-enhanced
computerized tomography, positron emission tomography (PET), and single-photon …
computerized tomography, positron emission tomography (PET), and single-photon …
[HTML][HTML] Targeting the SARS-CoV-2 HR1 with small molecules as inhibitors of the fusion process
The rapid and global propagation of the novel human coronavirus that causes severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has produced an immediate urgency to …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has produced an immediate urgency to …
[HTML][HTML] 1, 2-Dibenzoylhydrazine as a multi-inhibitor compound: A morphological and docking study
In the framework of the multitarget inhibitor study, we report an in silico analysis of 1, 2-
dibenzoylhydrazine (DBH) with respect to three essential receptors such as the ecdysone …
dibenzoylhydrazine (DBH) with respect to three essential receptors such as the ecdysone …
Artificial intelligence in medicine and dentistry
Sažetak Introduction: Artificial intelligence has been applied in various fields throughout
history, but its integration into daily life is more recent. The first applications of AI were …
history, but its integration into daily life is more recent. The first applications of AI were …
[HTML][HTML] Lessons learnt from COVID-19: computational strategies for facing present and future pandemics
Since its outbreak in December 2019, the COVID-19 pandemic has caused the death of
more than 6.5 million people around the world. The high transmissibility of its causative …
more than 6.5 million people around the world. The high transmissibility of its causative …
[HTML][HTML] Tribulations and future opportunities for artificial intelligence in precision medicine
C Carini, AA Seyhan - Journal of Translational Medicine, 2024 - Springer
Upon a diagnosis, the clinical team faces two main questions: what treatment, and at what
dose? Clinical trials' results provide the basis for guidance and support for official protocols …
dose? Clinical trials' results provide the basis for guidance and support for official protocols …
Recent advances in automated structure-based de novo drug design
As the number of determined and predicted protein structures and the size of druglike 'make-
on-demand'libraries soar, the time-consuming nature of structure-based computer-aided …
on-demand'libraries soar, the time-consuming nature of structure-based computer-aided …