The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Background Mild cognitive impairment (MCI) depicts a transitory phase between healthy
elderly and the onset of Alzheimer's disease (AD) with worsening cognitive impairment …

Prior randomized control trials have shown that cognitive training interventions resulted in
improved proximal task performance, improved functioning of activities of daily living, and …

Cognitive Reserve (CR) is considered a protective factor during the aging process.
However, although CR is a multifactorial construct, it has been operationalized in a unitary …

Normal aging is characterized by structural and functional changes in the brain contributing
to cognitive decline. Structural connectivity (SC) describes the anatomical backbone linking …

Epidemiological studies have shown that Parkinson's disease (PD) patients with probable
REM sleep behavior disorder (pRBD) present an increased risk of worse cognitive …

The relationships between aging and brain morphology have been reported in many
previous structural brain studies. However, the trajectories of successful brain aging in the …

Magnetic resonance imaging (MRI) studies of brain and neurocognitive aging rarely include
oldest-old adults (ages 80+). But predictions of neurocognitive aging theories derived from …

Background: The early detection of neurocognitive disorders, especially when mild, is a key
issue of health care systems including the Italian Dementia National Plan. The Mini-Mental …

The role of microbiota-gut-brain axis in modulating longevity remains undetermined. Here,
we performed a multiomics analysis of gut metagenomics, gut metabolomics, and brain …