The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

Wheat is widely available in people's daily diets. However, some people are currently
experiencing IgE-mediated allergic reactions to wheat-based foods, which seriously impact …

We introduce a versatile strategy for the bioreversible modification of proteins. Our strategy
is based on a tricomponent molecule, synthesized in three steps, that incorporates a diazo …

Achieving the full potential of therapeutic proteins to access and target intracellular receptors
will have enormous benefits in advancing human health and fighting disease. Existing …

Protein therapeutics targeting intracellular machineries hold profound potential for disease
treatment, and hence robust cytosolic protein delivery technologies are imperatively …

Protein therapeutics are of widespread interest due to their successful performance in the
current pharmaceutical and medical fields, even though their broad applications have been …

Rational design of efficient cytosolic protein delivery carriers holds enormous promise for
biotherapeutics development. Several delivery systems have been developed during the …

Antimicrobial peptides (AMPs) often display guanidinium functionalities, and hence robust
synthetic procedures are needed to facilitate access to analogues with unnatural …

Therapeutic outcomes of local biomolecule delivery to the central nervous system (CNS)
using bulk biomaterials are limited by inadequate drug loading, neuropil disruption, and …

In recent years, intracellular delivery of protein drugs has attracted great attention, and
polymer-based systems have been extensively exploited to develop efficient and safe …