[HTML][HTML] ACE2 and TMPRSS2 SNPs as Determinants of Susceptibility to, and Severity of, a COVID-19 Infection

S Abdelsattar, ZA Kasemy, SF Ewida… - British Journal of …, 2022 - frontierspartnerships.org
Background: Genetic risk factors may be related to the infectivity and severity of SARS-CoV-
2 infection. Angiotensin-converting enzyme 2 (ACE2) and host transmembrane serine …

[HTML][HTML] Hypotheses and facts for genetic factors related to severe COVID-19

SV Kotsev, D Miteva, S Krayselska… - World journal of …, 2021 - ncbi.nlm.nih.gov
Genome-wide association analysis allows the identification of potential candidate genes
involved in the development of severe coronavirus disease 2019 (COVID-19). Hence, it …

COVID-19: impact on Public Health and hypothesis-driven investigations on genetic susceptibility and severity

S David, G Dorado, EL Duarte, S David-Bosne… - Immunogenetics, 2022 - Springer
COVID-19 is a new complex multisystem disease caused by the novel coronavirus SARS-
CoV-2. In slightly over 2 years, it infected nearly 500 million and killed 6 million human …

Routine hematological parameters may be predictors of COVID-19 severity

PB Szklanna, H Altaie, SP Comer, S Cullivan… - Frontiers in …, 2021 - frontiersin.org
To date, coronavirus disease 2019 (COVID-19) has affected over 100 million people
globally. COVID-19 can present with a variety of different symptoms leading to manifestation …

Association between angiotensin-converting enzyme-2 gene polymorphism (rs2106809) with severity and outcome of COVID-19 infection

H Mohammadi-Berenjestanaki, E Mohammadali… - Molecular Biology …, 2023 - Springer
Purpose Genetic factors play important role in the severity of the COVID-19 infection since
SARS-CoV-2 binds to the ACE2 receptor on the surface of host cells. ACE2 polymorphisms …

Association of programmed cell death 1 (PD-1) gene polymorphism (rs10204525) with COVID-19 severity and mortality: A case-control study in the Iranian population

ES Mirsharif, A Rostamian, M Salehi, N Askari… - International …, 2023 - Elsevier
Background Programmed cell death 1 (PD-1), as a negative immune regulator, regulates the
activation of T cells and maintains the immune system's homeostasis. Previous studies …

The relationship of laboratory parameters and rates with prognosis and mortality in COVID-19 infection

H Ergenç, Z Ertürk, İH Tör, S Araç… - … of Biotechnology and …, 2022 - dergipark.org.tr
Objective: In this study, to evaluate the clinical course and prognosis in COVID-19 patients,
to evaluate the hematological and biochemical parameters at the time of admission to the …

[HTML][HTML] Influenza Viruses: Targetting Conserved Viral Ha-Stem, Matrix and Nucleo-Proteins to Disarm a Resilient and Recurring Pandemic

BO Oladejo, CF Adeboboye - RNA Viruses Infection, 2022 - intechopen.com
Much to the current worldwide pandemic caused by the SARs-Cov-2 virus, common flu
caused by Influenza virus remain a long-standing mayhem to global health. Influenza …

Dynamic Modeling of Antibody Repertoire Reshaping in Response to Viral Infections

Z Xu, J Xu, J Song, H Zhang, D Wei, Q Zeng, K Bryant - bioRxiv, 2024 - biorxiv.org
For many years, researchers have emphasized the production of high-affinity specific
antibodies by hosts during viral infections. However, this has made it challenging for …

Genotype and phenotype correlations in COVID-19

KR Anu, S Das, A Joseph - Omics approaches and technologies in COVID …, 2023 - Elsevier
SARS-CoV-2 is a chronic pneumonia-like infection reported first in 2019 December in the
Wuhan province of China. Several genetic factors found to play a part in the incidence and …