Background Chemoresistance to cisplatin (DDP) remains a major challenge in advanced
gastric cancer (GC) treatment. Although accumulating evidence suggests an association …

The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …

Resistance to chemotherapy remains one of the most significant obstacles to successful
cancer treatment. While inhibiting drug efflux mediated by ATP-binding cassette (ABC) …

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide, with high
recurrence and mortality rate. Chemotherapy, including 5-fluorouracil (5-FU), adriamycin …

The development of novel therapeutic approaches is necessary to manage gastrointestinal
cancers (GICs). Considering the effective molecular mechanisms involved in tumor growth …

The classic understanding of molecular disease-mechanisms is largely based on protein-
centric models. During the past decade however, genetic studies have identified numerous …

Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Glioma, as one of the most severe human malignancies, is defined as the Central Nervous
System's (CNS) tumors. Glioblastoma (GBM) in this regard, is the most malignant type of …