SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Humoral innate immunity and acute-phase proteins

A Mantovani, C Garlanda - New England Journal of Medicine, 2023 - Mass Medical Soc
Humoral Innate Immunity and Acute-Phase Proteins | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Effect of high-flow oxygen therapy vs conventional oxygen therapy on invasive mechanical ventilation and clinical recovery in patients with severe COVID-19: a …

GA Ospina-Tascón, LE Calderón-Tapia, AF García… - Jama, 2021 - jamanetwork.com
Importance The effect of high-flow oxygen therapy vs conventional oxygen therapy has not
been established in the setting of severe COVID-19. Objective To determine the effect of …

The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

Severe covid-19 pneumonia: pathogenesis and clinical management

AH Attaway, RG Scheraga, A Bhimraj, M Biehl… - bmj, 2021 - bmj.com
Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study

Intensive care medicine, 2021 - Springer
Purpose To describe acute respiratory distress syndrome (ARDS) severity, ventilation
management, and the outcomes of ICU patients with laboratory-confirmed COVID-19 and to …

Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

CL Walsh, P Tafforeau, WL Wagner, DJ Jafree… - Nature …, 2021 - nature.com
Imaging intact human organs from the organ to the cellular scale in three dimensions is a
goal of biomedical imaging. To meet this challenge, we developed hierarchical phase …

[HTML][HTML] The spatial landscape of lung pathology during COVID-19 progression

AF Rendeiro, H Ravichandran, Y Bram, V Chandar… - Nature, 2021 - nature.com
Recent studies have provided insights into the pathology of and immune response to COVID-
19,,,,,,–. However, a thorough investigation of the interplay between infected cells and the …

Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study

A Rouzé, I Martin-Loeches, P Povoa, D Makris… - Intensive care …, 2021 - Springer
Purpose Although patients with SARS-CoV-2 infection have several risk factors for ventilator-
associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital …