COVID-19 coagulopathy: from pathogenesis to treatment

T Alnima, MMG Mulder, BCT van Bussel… - Acta …, 2022 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) has emerged as a pandemic at the end of
2019 and continues to exert an unfavorable worldwide health impact on a large proportion …

Self-supervised contrastive learning for integrative single cell RNA-seq data analysis

W Han, Y Cheng, J Chen, H Zhong, Z Hu… - Briefings in …, 2022 - academic.oup.com
We present a novel self-supervised Contrastive LEArning framework for single-cell
ribonucleic acid (RNA)-sequencing (CLEAR) data representation and the downstream …

[HTML][HTML] Biomarkers of the ageing immune system and their association with frailty–A systematic review

ET Van Hoi, NA De Glas, JEA Portielje… - Experimental …, 2023 - Elsevier
Introduction Ageing is associated with several physiological changes, including changes in
the immune system. Age-related changes in the innate and adaptive immune system are …

[HTML][HTML] Identification of parameters representative of immune dysfunction in patients with severe and fatal COVID-19 infection: a systematic review and meta-analysis

R Qin, L He, Z Yang, N Jia, R Chen, J Xie, W Fu… - Clinical Reviews in …, 2023 - Springer
Abnormal immunological indicators associated with disease severity and mortality in
patients with COVID-19 have been reported in several observational studies. However …

[HTML][HTML] SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells

N Huot, C Planchais, P Rosenbaum, V Contreras… - Nature …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes
undetectable in upper airways after a few days or weeks postinfection. Here we used a …

Immunopharmacological perspective on zinc in SARS-CoV-2 infection

SH Asl, S Nikfarjam, NM Zolbanin, R Nassiri… - International …, 2021 - Elsevier
The novel SARS-CoV-2 which was first reported in China is the cause of infection known as
COVID-19. In comparison with other coronaviruses such as SARS-CoV and MERS, the …

[HTML][HTML] Role of OAS gene family in COVID-19 induced heart failure

LJ Gao, ZM He, YY Li, RR Yang, M Yan… - Journal of Translational …, 2023 - Springer
Background COVID-19, the current global pandemic caused by SARS-CoV-2 infection, can
damage the heart and lead to heart failure (HF) and even cardiac death. The 2', 5' …

Prostaglandins and non-steroidal anti-inflammatory drugs in Covid-19

HM Al-Kuraishy, AI Al-Gareeb… - Biotechnology and …, 2022 - Taylor & Francis
In response to different viral infections, including SARS-CoV-2 infection, pro-inflammatory,
anti-inflammatory cytokines, and bioactive lipids are released from infected and immune …

[HTML][HTML] Cytokine storm-calming property of the isoquinoline alkaloids in Coptis chinensis Franch

Y Lan, H Wang, J Wu, X Meng - Frontiers in pharmacology, 2022 - frontiersin.org
Coronavirus disease (COVID-19) has spread worldwide and its effects have been more
devastating than any other infectious disease. Importantly, patients with severe COVID-19 …

[PDF][PDF] COVID-19 pandemic sheds a new research spotlight on antiviral potential of essential oils–A bibliometric study

B Ginting, W Chiari, TF Duta, S Hudaa, A Purnama… - Heliyon, 2023 - cell.com
Background Essential oils are thought as potential therapies in managing coronavirus
disease 2019 (COVID-19). Many researchers have put their efforts to tackle the pandemic by …