[HTML][HTML] Epigenetic control of skeletal muscle atrophy
W Liang, F Xu, L Li, C Peng, H Sun, J Qiu… - Cellular & Molecular …, 2024 - Springer
Skeletal muscular atrophy is a complex disease involving a large number of gene
expression regulatory networks and various biological processes. Despite extensive …
expression regulatory networks and various biological processes. Despite extensive …
[HTML][HTML] Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway
J Sun, H Zhou, Z Chen, H Zhang, Y Cao, X Yao… - Journal of Translational …, 2023 - Springer
Background Denervation-induced muscle atrophy is complex disease involving multiple
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
[HTML][HTML] IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), with high affinity to a myriad
of RNA transcripts, has been shown to elicit promotive effects on tumorigenesis and …
of RNA transcripts, has been shown to elicit promotive effects on tumorigenesis and …
Exploring the role of m7G modification in Cancer: Mechanisms, regulatory proteins, and biomarker potential
Y Zhang, W Xu, C Peng, S Ren, SM Hidig, C Zhang - Cellular Signalling, 2024 - Elsevier
Abstract The dysregulation of N (7)-methylguanosine (m7G) modification is increasingly
recognized as a key factor in the pathogenesis of cancers. Aberrant expression of these …
recognized as a key factor in the pathogenesis of cancers. Aberrant expression of these …
[HTML][HTML] A novel lncRNA LOC101928222 promotes colorectal cancer angiogenesis by stabilizing HMGCS2 mRNA and increasing cholesterol synthesis
L Chang, J Ding, J Pu, J Zhu, X Zhou, Q Luo… - Journal of Experimental …, 2024 - Springer
Background Metastasis is the leading cause of mortality in patients with colorectal cancer
(CRC) and angiogenesis is a crucial factor in tumor invasion and metastasis. Long …
(CRC) and angiogenesis is a crucial factor in tumor invasion and metastasis. Long …
[HTML][HTML] A novel signature constructed by cuproptosis-related RNA methylation regulators suggesting downregulation of YTHDC2 may induce cuproptosis resistance …
Z Zhao, Z Miao, Y Hou, Y Zhong, X Zhang… - International …, 2024 - Elsevier
Background A newly identified type of cell death due to intracellular copper accumulation is
known as cuproptosis and RNA methylation is a post-transcriptional modification …
known as cuproptosis and RNA methylation is a post-transcriptional modification …
[HTML][HTML] Mechanisms and clinical landscape of N6-methyladenosine (m6A) RNA modification in gastrointestinal tract cancers
DH Zhu, KK Su, XX Ou-Yang, YH Zhang, XP Yu… - Molecular and Cellular …, 2024 - Springer
Epigenetics encompasses reversible and heritable chemical modifications of non-nuclear
DNA sequences, including DNA and RNA methylation, histone modifications, non-coding …
DNA sequences, including DNA and RNA methylation, histone modifications, non-coding …
Fat mass and obesity-associated protein inhibit the pathology of rheumatoid arthritis through the NSUN2/SFRP1/Wnt/β-catenin signal axis
Y Huang, P Xu, F Liao, H Ca, X Wang… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives The purpose of this study is to investigate whether fat mass and obesity-
associated protein (FTO) and NOL1/NOP2/Sun domain family member 2 (NSUN2) mediated …
associated protein (FTO) and NOL1/NOP2/Sun domain family member 2 (NSUN2) mediated …