COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation

D Kempuraj, GP Selvakumar, ME Ahmed… - The …, 2020 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …

Molnupiravir: A new candidate for COVID‐19 treatment

F Pourkarim, S Pourtaghi‐Anvarian… - Pharmacology …, 2022 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) emerged in late December 2019 in china
and has rapidly spread to many countries around the world. The effective pharmacotherapy …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
COVID-19–associated morbidity and mortality have been attributed to a pathologic host
response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine …

Novel canine coronavirus isolated from a hospitalized patient with pneumonia in East Malaysia

AN Vlasova, A Diaz, D Damtie, L Xiu… - Clinical Infectious …, 2022 - academic.oup.com
Background During the validation of a highly sensitive panspecies coronavirus (CoV)
seminested reverse-transcription polymerase chain reaction (RT-PCR) assay, we found …

Food irradiation: Effect of ionizing and non-ionizing radiations on preservation of fruits and vegetables–a review

B Bisht, P Bhatnagar, P Gururani, V Kumar… - Trends in Food Science …, 2021 - Elsevier
Background Food irradiation is a non-thermal, energy-efficient, non-chemical and physical
method of food preservation in which the food is exposed to various ionizing and non …

X-ray and CT-scan-based automated detection and classification of covid-19 using convolutional neural networks (CNN)

S Thakur, A Kumar - Biomedical Signal Processing and Control, 2021 - Elsevier
Abstract Covid-19 (Coronavirus Disease-2019) is the most recent coronavirus-related
disease that has been announced as a pandemic by the World Health Organization (WHO) …

[HTML][HTML] The role of type I interferons in the pathogenesis and treatment of COVID-19

G Schreiber - Frontiers in immunology, 2020 - frontiersin.org
Type I interferons (IFN-I) were first discovered over 60 years ago in a classical experiment by
Isaacs and Lindenman, who showed that IFN-Is possess antiviral activity. Later, it became …

A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins

J Zhang, R Cruz-Cosme, MW Zhuang, D Liu… - Signal transduction and …, 2020 - nature.com
The current pandemic of beta-coronavirus (SARS-CoV-2) has exerted devastating influence
on almost all countries, resulting in the disease named COVID-19. 1 Coronavirus possesses …

[HTML][HTML] Catalytic dyad residues His41 and Cys145 impact the catalytic activity and overall conformational fold of the main SARS-CoV-2 protease 3-chymotrypsin-like …

JC Ferreira, S Fadl, AJ Villanueva, WM Rabeh - Frontiers in chemistry, 2021 - frontiersin.org
Coronaviruses are responsible for multiple pandemics and millions of deaths globally,
including the current pandemic of coronavirus disease 2019 (COVID-19). Development of …

SARS-Cov-2 ORF3a: mutability and function

M Bianchi, A Borsetti, M Ciccozzi… - International journal of …, 2021 - Elsevier
In this study, analysis of changes of SARS-CoV-2 ORF3a protein during pandemic is
reported. ORF3a, a conserved coronavirus protein, is involved in virus replication and …