The dialogue between neuroinflammation and adult neurogenesis: mechanisms involved and alterations in neurological diseases

M Amanollahi, M Jameie, A Heidari, N Rezaei - Molecular neurobiology, 2023 - Springer
Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

Exercise suppresses neuroinflammation for alleviating Alzheimer's disease

M Wang, H Zhang, J Liang, J Huang… - Journal of …, 2023 - Springer
Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice

N Kim, SH Jeon, IG Ju, MS Gee, J Do, MS Oh… - Brain, Behavior, and …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that causes memory and cognitive
decline. Although many studies have attempted to clarify the causes of AD occurrence, it is …

Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?

G Tosoni, D Ayyildiz, J Bryois, W Macnair… - Neuron, 2023 - cell.com
The notion of exploiting the regenerative potential of the human brain in physiological aging
or neurological diseases represents a particularly attractive alternative to conventional …

Inflammatory processes in alzheimer's disease—pathomechanism, diagnosis and treatment: a review

B Twarowski, M Herbet - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease is one of the most commonly diagnosed cases of senile dementia in the
world. It is an incurable process, most often leading to death. This disease is multifactorial …

[HTML][HTML] New insights into the role and mechanisms of ginsenoside Rg1 in the management of Alzheimer's disease

J Wu, Y Yang, Y Wan, J Xia, JF Xu, L Zhang… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disorder in the elderly
characterized by memory loss and cognitive dysfunction. The pathogenesis of AD is …

Neurogenesis after stroke: a therapeutic perspective

AA Rahman, N Amruta, E Pinteaux, GJ Bix - Translational stroke research, 2021 - Springer
Stroke is a major cause of death and disability worldwide. Yet therapeutic strategies
available to treat stroke are very limited. There is an urgent need to develop novel …

Memantine, donepezil, or combination therapy—What is the best therapy for Alzheimer's disease? A network meta‐analysis

J Guo, Z Wang, R Liu, Y Huang, N Zhang… - Brain and …, 2020 - Wiley Online Library
Introduction Alzheimer's disease (AD) is a degenerative brain disease that progresses over
time, heavily burdening patients, families, and aging societies worldwide. Memantine and …

Role of JAK/STAT in the neuroinflammation and its association with neurological disorders

M Jain, MK Singh, H Shyam, A Mishra… - Annals of …, 2021 - journals.sagepub.com
Background: Innate immunity is mediated by a variety of cell types, including microglia,
macrophages, and neutrophils, and serves as the immune system's first line of defense …

Overview of the role of vanillin in neurodegenerative diseases and neuropathophysiological conditions

C Iannuzzi, M Liccardo, I Sirangelo - International Journal of Molecular …, 2023 - mdpi.com
Nowadays, bioactive natural products play key roles in drug development due to their safety
profile and strong antioxidant power. Vanillin is a natural phenolic compound found in …