Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging
Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …
on patterns of DNA methylation—can be computed and is associated with an array of factors …
Significance of psychosocial factors in cardiology: update 2018: Position paper of the German Cardiac Society
C Albus, C Waller, K Fritzsche, H Gunold… - Clinical Research in …, 2019 - Springer
Background Psychosocial factors in cardiovascular diseases are increasingly
acknowledged by patients, health care providers and payer organizations. Due to the rapidly …
acknowledged by patients, health care providers and payer organizations. Due to the rapidly …
GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality
The aging process is characterized by the presence of high interindividual variation between
individuals of the same chronical age prompting a search for biomarkers that capture this …
individuals of the same chronical age prompting a search for biomarkers that capture this …
DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: The DAMA study
Several biomarkers of healthy aging have been proposed in recent years, including the
epigenetic clocks, based on DNA methylation (DNAm) measures, which are getting …
epigenetic clocks, based on DNA methylation (DNAm) measures, which are getting …
Cohort profile update: the Irish longitudinal study on ageing (TILDA)
OA Donoghue, CA McGarrigle, M Foley… - International journal …, 2018 - academic.oup.com
As outlined in the original cohort profile, 1 The Irish Longitudinal Study on Ageing (TILDA) is
a prospective cohort study designed to provide an evidence base for addressing the …
a prospective cohort study designed to provide an evidence base for addressing the …
The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health
CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
[HTML][HTML] Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis
Differences in health status by socioeconomic position (SEP) tend to be more evident at
older ages, suggesting the involvement of a biological mechanism responsive to the …
older ages, suggesting the involvement of a biological mechanism responsive to the …
Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics
The largest US cancer health disparity exists in prostate cancer, with Black men having more
than a two-fold increased risk of dying from prostate cancer compared to all other races. This …
than a two-fold increased risk of dying from prostate cancer compared to all other races. This …
DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva …
Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration
(EGAA) are biomarkers of physiological development and may be affected by the perinatal …
(EGAA) are biomarkers of physiological development and may be affected by the perinatal …