Objective To explore the cumulative genotoxic damage to glioblastoma (GBM) cells, grown
as multicellular spheroids, following exposure to 6 MV X-rays (2 Gy, 22 Gy) with or without, 2 …

The HYP‐RT model simulates hypoxic tumour growth for head and neck cancer as well as
radiotherapy and the effects of accelerated repopulation and reoxygenation. This report …

The tremendous rate of accumulation of experimentally and clinically extracted knowledge
concerning cancer at all levels of biocomplexity dictates the development of integrative in …

We propose the modeling of glioblastoma isocitrate dehydrogenase wild-type (GBMwt) build
on the following hypotheses: the brain tissue is a porous medium, the coupling of hypoxia …

The basis of this work is the reactive multiphase poromechanical model developed since
2013 by Sciumè et al. A porous system is modelled as a porous solid saturated by two or …

In silico modeling of tumor growth and treatment response within the ContraCancrum
oncosimulator context requires a specific handling of the molecular variation of patient …

Tumour hypoxia is the inadequate supply of oxygen in living tissue. Hypoxia is a major
problem in the treatment cancer with ionising radiation because of the associated increase …

O cancro foi, segundo os dados apresentados em 2018, pela Organização Mundial de
Saúde, um dos grandes flagelos da humanidade e constituiu a segunda causa de morte …

The contracancrum oncosimulator: integrating biomechanisms across scales in the clinical
context Page 76 68 G. Stamatakos and D. Dionysiou (Eds): Proc. 4th Int. A dv. Res. Work …

The war against cancer continues to take its toll on society, even after many decades of
focused, intensive research into its origins and cures. Increasingly, efforts are being made to …