Pharmacological therapies and drug development targeting SARS-CoV-2 infection

Y Jiang, L Rubin, Z Zhou, H Zhang, Q Su… - Cytokine & Growth …, 2022 - Elsevier
The development of therapies for SARS-CoV-2 infection, based on virus biology and
pathology, and of large-and small-scale randomized controlled trials, have brought forward …

Relapses of idiopathic inflammatory myopathies after vaccination against COVID-19: a real-life multicenter Italian study

E Conticini, M d'Alessandro, S Grazzini… - Internal and Emergency …, 2022 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination plays a crucial
role as pivotal strategy to curb the coronavirus disease-19 (COVID-19) pandemic. The …

Influenza and COVID-19 co-infection and vaccine effectiveness against severe cases: a mathematical modeling study

J Liang, Y Wang, Z Lin, W He, J Sun, Q Li… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Influenza A virus have a distinctive ability to exacerbate SARS-CoV-2 infection
proven by in vitro studies. Furthermore, clinical evidence suggests that co-infection with …

Effectiveness and safety of COVID-19 vaccines on maternal and perinatal outcomes: a systematic review and meta-analysis

S Fernández-García, L del Campo-Albendea… - BMJ Global …, 2024 - gh.bmj.com
Objective To assess the effects of COVID-19 vaccines in women before or during pregnancy
on SARS-CoV-2 infection-related, pregnancy, offspring and reactogenicity outcomes …

Public health impact of the Pfizer-BioNTech COVID-19 vaccine (BNT162b2) in the first year of rollout in the United States

M Di Fusco, K Marczell, KA Deger… - Journal of Medical …, 2022 - Taylor & Francis
Background As the body of evidence on COVID-19 and post-vaccination outcomes
continues to expand, this analysis sought to evaluate the public health impact of the Pfizer …

Protective effect of inactivated COVID-19 vaccines against progression of SARS-CoV-2 Omicron and delta variant infections to pneumonia in Beijing, China, in 2022

J Li, R Song, Z Yuan, Z Xu, L Suo, Q Wang, Y Li, Y Gao… - Vaccines, 2022 - mdpi.com
This real-world study explores the effect of coronavirus disease 2019 (COVID-19)
inactivated vaccines on the prevention of asymptomatic or mild Delta or Omicron variant …

Efficacy of COVID-19 vaccines: a systematic review and network meta-analysis of phase 3 randomized controlled trials

S Kumar, D Saikia, M Bankar, MK Saurabh… - Pharmacological …, 2022 - Springer
Several vaccines have been approved for the prevention of COVID-19. However, no head-to-
head trials comparing their clinical efficacy have been performed. This network meta …

Humoral and cellular response to the COVID-19 vaccine in immunocompromised children

HA Morgans, T Bradley, L Flebbe-Rehwaldt… - Pediatric …, 2023 - nature.com
Background A suboptimal response to the 2-dose COVID-19 vaccine series in the
immunocompromised population prompted recommendations for a 3rd primary dose. We …

Sudan Ebola virus (SUDV) outbreak in Uganda, 2022: lessons learnt and future priorities for sub-Saharan Africa

G Bwire, B Sartorius, P Guerin, MA Tegegne… - BMC medicine, 2023 - Springer
Background On 20th September 2022, the Ugandan Ministry of Health (MOH) declared an
outbreak of haemorrhagic fever caused by the Sudan Ebola virus (SUDV) following …

Systematic down-selection of repurposed drug candidates for COVID-19

CA MacRaild, MUR Mohammed, Faheem… - International journal of …, 2022 - mdpi.com
SARS-CoV-2 is the cause of the COVID-19 pandemic which has claimed more than 6.5
million lives worldwide, devastating the economy and overwhelming healthcare systems …