TOMM40 genetic variants associated with healthy aging and longevity: a systematic review

S Chen, SM Sarasua, NJ Davis, JM DeLuca, L Boccuto… - BMC geriatrics, 2022 - Springer
Introduction Healthy aging relies on mitochondrial functioning because this organelle
provides energy and diminishes oxidative stress. Single nucleotide polymorphisms (SNPs) …

[HTML][HTML] Footprints in the sand: deep taxonomic comparisons in vertebrate genomics to unveil the genetic programs of human longevity

S Treaster, D Karasik, MP Harris - Frontiers in Genetics, 2021 - frontiersin.org
With the modern quality, quantity, and availability of genomic sequencing across species, as
well as across the expanse of human populations, we can screen for shared signatures …

[HTML][HTML] Association of inflammatory markers with muscle and cognitive function in early and late-aging older adults

NS Haeri, S Perera, NK Nadkarni… - The Journal of nutrition …, 2024 - Elsevier
Objectives Age-related loss in muscle and cognitive function is common in older adults.
Numerous studies have suggested that inflammation contributes to the decline in physical …

[PDF][PDF] TOMM40 genetic variants associated with healthy aging and longevity: a systematic

S Chen, SM Sarasua, NJ Davis, JM DeLuca… - 2022 - bmcgeriatr.biomedcentral.com
Introduction: Healthy aging relies on mitochondrial functioning because this organelle
provides energy and dimin‑ishes oxidative stress. Single nucleotide polymorphisms (SNPs) …

Weight Maintenance, a Prognostic Factor That Mediates the Incidence of Dementia: From Genetics to Etiologies

S Chen - 2022 - tigerprints.clemson.edu
Objectives: Alzheimer's disease-related dementia is a devastating neurodegenerative
disease that affects millions of people. The goal of this work is to investigate biological …

A molecular index for biological age identified from the metabolome and senescence‐associated secretome in humans

S Hamsanathan, T Anthonymuthu, D Prosser… - Aging …, 2024 - Wiley Online Library
Unlike chronological age, biological age is a strong indicator of health of an individual.
However, the molecular fingerprint associated with biological age is ill‐defined. To define a …