The harmful COVID-19 pandemic caused by the SARS-CoV-2 coronavirus imposes the scientific community to develop or find conventional curative drugs, protective vaccines, or …
AK Verma - Journal of Biomolecular Structure and Dynamics, 2022 - Taylor & Francis
Spike protein and main proteases of SARS-CoV-2 have been identified as potential therapeutic targets and their inhibition may lead to the reticence of viral entry and replication …
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel coronavirus, has brought an unprecedented pandemic to the world and affected over 64 million people. The …
Abstract The SARS-CoV-2 3CL protease (3CLpro) shows a high similarity with 3CL proteases of other beta-coronaviruses, such as SARS and MERS. It is the main enzyme …
M Kircher, E Chludzinski, J Krepel, B Saremi… - International journal of …, 2022 - mdpi.com
To better understand the molecular basis of respiratory diseases of viral origin, high- throughput gene-expression data are frequently taken by means of DNA microarray or RNA …
K Slater, JA Williams, PN Schofield, S Russell… - Computers in Biology …, 2023 - Elsevier
Annotation of biomedical entities with ontology classes provides for formal semantic analysis and mobilisation of background knowledge in determining their relationships. To date …
P Kumari, R Poddar - Computational Biology and Chemistry, 2021 - Elsevier
Zoonotic Novel coronavirus disease 2019 (COVID-19) is highly pathogenic and transmissible considered as emerging pandemic disease. The virus belongs from a large …
Functional enrichment analysis is an essential downstream process in high throughput omics studies, such as transcriptomics and proteomics. By using the Gene Ontology (GO) …