The effect of quercetin supplementation on clinical outcomes in COVID‐19 patients: A systematic review and meta‐analysis

S Ziaei, M Alimohammadi‐Kamalabadi… - Food Science & …, 2023 - Wiley Online Library
Abstract Coronavirus disease (COVID‐19) affects both the respiratory system and the body
as a whole. Natural molecules, such as flavonoid quercetin, as potential treatment methods …

A review of monoclonal antibodies in COVID-19: Role in immunotherapy, vaccine development and viral detection

AA Tabll, YE Shahein, MM Omran… - Human …, 2021 - content.iospress.com
The harmful COVID-19 pandemic caused by the SARS-CoV-2 coronavirus imposes the
scientific community to develop or find conventional curative drugs, protective vaccines, or …

Cordycepin: a bioactive metabolite of Cordyceps militaris and polyadenylation inhibitor with therapeutic potential against COVID-19

AK Verma - Journal of Biomolecular Structure and Dynamics, 2022 - Taylor & Francis
Spike protein and main proteases of SARS-CoV-2 have been identified as potential
therapeutic targets and their inhibition may lead to the reticence of viral entry and replication …

In silico binding profile characterization of SARS-CoV-2 spike protein and its mutants bound to human ACE2 receptor

Y Zhang, X He, J Zhai, B Ji, VH Man… - Briefings in …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel coronavirus, has
brought an unprecedented pandemic to the world and affected over 64 million people. The …

[HTML][HTML] Nucleocapsid and spike proteins of SARS-CoV-2 drive neutrophil extracellular trap formation

YJ Youn, YB Lee, SH Kim, HK Jin, J Bae… - Immune …, 2021 - ncbi.nlm.nih.gov
Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated
immune responses including exacerbated neutrophil functions. Massive neutrophil …

Proposition of a new allosteric binding site for potential SARS-CoV-2 3CL protease inhibitors by utilizing molecular dynamics simulations and ensemble docking

J Novak, H Rimac, S Kandagalla, P Pathak… - Journal of …, 2022 - Taylor & Francis
Abstract The SARS-CoV-2 3CL protease (3CLpro) shows a high similarity with 3CL
proteases of other beta-coronaviruses, such as SARS and MERS. It is the main enzyme …

Augmentation of transcriptomic data for improved classification of patients with respiratory diseases of viral origin

M Kircher, E Chludzinski, J Krepel, B Saremi… - International journal of …, 2022 - mdpi.com
To better understand the molecular basis of respiratory diseases of viral origin, high-
throughput gene-expression data are frequently taken by means of DNA microarray or RNA …

[HTML][HTML] Klarigi: Characteristic explanations for semantic biomedical data

K Slater, JA Williams, PN Schofield, S Russell… - Computers in Biology …, 2023 - Elsevier
Annotation of biomedical entities with ontology classes provides for formal semantic analysis
and mobilisation of background knowledge in determining their relationships. To date …

A computational analysis of molecular evolution for virulence genes of zoonotic novel coronavirus (COVID-19)

P Kumari, R Poddar - Computational Biology and Chemistry, 2021 - Elsevier
Zoonotic Novel coronavirus disease 2019 (COVID-19) is highly pathogenic and
transmissible considered as emerging pandemic disease. The virus belongs from a large …

[PDF][PDF] FAIR Functional Enrichment: Assessing and Modelling Provenance in Omics Results

Y Chen, FJ Verbeek, KJ Wolstencroft - Proceedings http://ceur-ws. org …, 2023 - ceur-ws.org
Functional enrichment analysis is an essential downstream process in high throughput
omics studies, such as transcriptomics and proteomics. By using the Gene Ontology (GO) …