Regulation of the immune response by TGF-β: from conception to autoimmunity and infection

S Sanjabi, SA Oh, MO Li - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) is a pleiotropic cytokine involved in both suppressive
and inflammatory immune responses. After 30 years of intense study, we have only begun to …

The role of Th17 cells in viral infections

PS Aghbash, N Hemmat, JS Nahand… - International …, 2021 - Elsevier
The present review provides an overview of recent advances regarding the function of Th17
cells and their produced cytokines in the progression of viral diseases. Viral infections alone …

Cytokines and chemokines in HBV infection

S Zhong, T Zhang, L Tang, Y Li - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a leading cause of hepatic inflammation
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …

Cytokine-mediated immunopathogenesis of hepatitis B virus infections

X Li, X Liu, L Tian, Y Chen - Clinical reviews in allergy & immunology, 2016 - Springer
Hepatitis B virus (HBV) infection is a worldwide health problem, with approximately one third
of populations have been infected, among which 3–5% of adults and more than 90% of …

Immune regulation by T regulatory cells in hepatitis B virus‐related inflammation and cancer

N Trehanpati, AK Vyas - Scandinavian journal of immunology, 2017 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the leading cause of cancer death, and hepatitis B virus
(HBV) infection is one of the commonest causes in Asian countries. India has the second …

[HTML][HTML] Virus-related liver cirrhosis: molecular basis and therapeutic options

J Lin, JF Wu, Q Zhang, HW Zhang… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Chronic infections with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) are the major
causes of cirrhosis globally. It takes 10-20 years to progress from viral hepatitis to cirrhosis …

Insights into the impact of hepatitis B virus on hepatic stellate cell activation

H You, X Wang, L Ma, F Zhang, H Zhang… - Cell Communication and …, 2023 - Springer
During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological
condition caused by virus-induced liver damage. The activation of hepatic stellate cells …

The study of the serum level of IL‐4, TGF‐β, IFN‐γ, and IL‐6 in overweight patients with and without diabetes mellitus and hypertension

G Asadikaram, M Ram, A Izadi… - Journal of Cellular …, 2019 - Wiley Online Library
Background Obesity increases the risk of diabetes mellitus (DM) and hypertension. We
aimed to analyze the serum levels of cytokines that have relevance to the pathologies …

Detection of hepatitis B surface antigen among febrile patients in Ankpa, Kogi State, Nigeria

CA Omatola, BA Onoja, J Agama - Journal of Tropical Medicine, 2020 - Wiley Online Library
Background. Hepatitis B virus (HBV) infection has become a significant public health
problem in developing countries, and the high rate of morbidity and mortality from acute and …

lncRNA-HEIM Facilitated Liver Fibrosis by Up-Regulating TGF-β Expression in Long-Term Outcome of Chronic Hepatitis B

J Yao, C Lin, J Jiang, X Zhang, F Li, T Liu… - Frontiers in …, 2021 - frontiersin.org
Background Chronic liver fibrosis is an inevitable stage for the development of patients with
chronic hepatitis B (CHB). However, anti-fibrotic therapies have been unsuccessful so far …