[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation

S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …

[HTML][HTML] The machinery of exosomes: biogenesis, release, and uptake

SV Krylova, D Feng - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

[HTML][HTML] Laboratory findings and biomarkers in long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and …

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Exosome-and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders

B Lu, J Ku, R Flojo, C Olson, D Bengford… - Advanced Drug Delivery …, 2022 - Elsevier
Cell-generated extracellular vesicles (EVs) are being engineered as biologically-inspired
vehicles for targeted delivery of therapeutic agents to treat difficult-to-manage human …

[PDF][PDF] COVID infection in 4 steps: Thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive …

M Popovic, JH Martin, RJ Head - Heliyon, 2023 - cell.com
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection,
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …

COVID-19 inflammation and implications in drug delivery

M Zoulikha, F Huang, Z Wu, W He - Journal of Controlled Release, 2022 - Elsevier
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …

[HTML][HTML] Pulmonary embolism in post-CoviD-19 patients, a literature review: red flag for increased awareness?

A Mouzarou, M Ioannou, E Leonidou… - SN comprehensive clinical …, 2022 - Springer
Although COVID-19 was primarily considered a respiratory illness, rapidly accumulating
data suggest that COVID-19 is associated with a high incidence of venous thromboembolic …

Genomic and structural mechanistic insight to reveal the differential infectivity of omicron and other variants of concern

P Sharma, M Kumar, MK Tripathi, D Gupta… - Computers in Biology …, 2022 - Elsevier
Background The genome of SARS-CoV-2, is mutating rapidly and continuously challenging
the management and preventive measures adopted and recommended by healthcare …

Therapeutic Applications of Stem Cell-Derived Exosomes

OAAY Abdulmalek, KH Husain, HKAA AlKhalifa… - International Journal of …, 2024 - mdpi.com
Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …