The rising tide of non-alcoholic fatty liver disease (NAFLD) associated with the obesity
epidemic is a major health concern worldwide. NAFLD—specifically its more advanced form …

With covalently closed circular structures, circular RNAs (circRNAs) were once
misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved …

Background Exosomes in the tumor microenvironment (TME) facilitate tumor progression by
enabling inter-cellular communication. Tumor cell-derived exosomes can polarize tumor …

Atherosclerosis (AS) is a chronic inflammatory lesion of the arterial vessel wall caused by a
variety of complex factors. Furthermore, it is a major cause of cardiovascular disease and a …

Abstract Purpose of Review Non-coding RNAs (ncRNAs) including microRNAs (miRNAs)
and circular RNAs (circRNAs) are pivotal regulators of mRNA and protein expression that …

Circular RNAs (circRNAs) are a class of noncoding RNAs with a covalently closed loop
structure. Recent evidence has shown that circRNAs can regulate gene transcription …

Atherosclerosis is a significant risk factor for coronary heart disease (CHD) and myocardial
infarction (MI). Atherosclerosis develops during foam cell generation, which is caused by an …

Tacrolimus (TAC)-based treatment is associated with nephrotoxicity and hepatotoxicity;
however, the underlying molecular mechanisms responsible for this toxicity have not been …

Simple Summary Intramuscular fat (IMF) is a key factor affecting many meat quality traits of
pigs, such as pork tenderness, flavor, and many more. In this study, a systematic …

Rapamycin is a crucial immunosuppressive regimen for patients that have undergone liver
transplantation (LT). However, one of the major side effects of rapamycin include metabolic …