Nerve regeneration using decellularized tissues: challenges and opportunities

M Mahdian, TS Tabatabai, Z Abpeikar… - Frontiers in …, 2023 - frontiersin.org
In tissue engineering, the decellularization of organs and tissues as a biological scaffold
plays a critical role in the repair of neurodegenerative diseases. Various protocols for cell …

[HTML][HTML] Exosomal Cargo: Pro-angiogeneic, anti-inflammatory, and regenerative effects in ischemic and non-ischemic heart diseases–A comprehensive review

A Ahmadi, MG Ahmadabadi, A Babajani… - Biomedicine & …, 2023 - Elsevier
Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

Wet-spinnability and crosslinked Fiber properties of alginate/hydroxyethyl cellulose with varied proportion for potential use in tendon tissue engineering

M Hojabri, T Tayebi, M Kasravi, A Aghdaee… - International Journal of …, 2023 - Elsevier
Researchers have examined different bio-inspired materials in tissue engineering and
regenerative medicine to fabricate scaffolds to address tendon regeneration requirements …

Conserved and tissue-specific immune responses to biologic scaffold implantation

S DeStefano, DR Hartigan, A Josyula, M Faust, D Fertil… - Acta Biomaterialia, 2024 - Elsevier
Upon implantation into a patient, any biomaterial induces a cascade of immune responses
that influences the outcome of that device. This cascade depends upon several factors …

MMP inhibition as a novel strategy for extracellular matrix preservation during whole liver decellularization

M Kasravi, A Yaghoobi, T Tayebi, M Hojabri… - Biomaterials …, 2024 - Elsevier
As the only reliable treatment option for end-stage liver diseases, conventional liver
transplantation confronts major supply limitations. Accordingly, the decellularization of …

Hydrogel-encapsulated extracellular vesicles for the regeneration of spinal cord injury

Y Nazerian, A Nazerian, F Mohamadi-Jahani… - Frontiers in …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a critical neurological condition that may impair motor, sensory,
and autonomous functions. At the cellular level, inflammation, impairment of axonal …

Functionalized acellular periosteum guides stem cell homing to promote bone defect repair

G Zhu, Y Zhou, Y Xu, L Wang, M Han, K Xi… - Journal of …, 2023 - Taylor & Francis
The periosteum plays a key role in bone tissue regeneration, especially in the promotion
and protection of new bones. However, among the bone repair materials, many biomimetic …

Integrated bioinformatics and wet-lab analysis revealed cell adhesion prominent genes CDC42, TAGLN and GSN as prognostic biomarkers in colonic-polyp lesions

ES Tabatabaei, R Mazloomnejad, L Rejali… - Scientific Reports, 2023 - nature.com
Colorectal cancers are derived from intestinal polyps. Normally, alterations in cell adhesion
genes expression cause deviation from the normal cell cycle, leading to cancer …

Bioactive injectable mucoadhesive thermosensitive natural polymeric hydrogels for oral bone and periodontal regeneration

M El-Nablaway, F Rashed, ES Taher… - … in Bioengineering and …, 2024 - frontiersin.org
Periodontitis is an inflammation-related condition, caused by an infectious microbiome and
host defense that causes damage to periodontium. The natural processes of the mouth, like …

Tissue‐engineered tracheal implants: Advancements, challenges, and clinical considerations

S Wei, Y Zhang, F Luo, K Duan, M Li… - … & Translational Medicine, 2024 - Wiley Online Library
Restoration of extensive tracheal damage remains a significant challenge in respiratory
medicine, particularly in instances stemming from conditions like infection, congenital …