Comparison of bivalent and monovalent mRNA vaccine boosters

CKH Wong, KTK Lau, ICH Au, EHY Lau… - Clinical Infectious …, 2024 - academic.oup.com
In this cohort study conducted in Hong Kong where both bivalent and monovalent
formulations of BNT162b2 were available, there were no significant differences in the …

[HTML][HTML] Effectiveness of azvudine in reducing mortality of COVID-19 patients: a systematic review and meta-analysis

Y Wang, H Xie, L Wang, J Fan, Y Zhang, S Pan… - Virology Journal, 2024 - Springer
Background Azvudine has been approved for the treatment of coronavirus disease 2019
(COVID-19) patients in China, and this meta-analysis aims to illustrate the safety of azvudine …

Effectiveness of mRNA BNT162b2 and inactivated CoronaVac vaccines against severe COVID-19 outcomes among non-hospitalised children aged 1-3 years with …

CKH Wong, KTK Lau, ICH Au, EHY Lau… - International Journal of …, 2024 - Elsevier
Objectives Clinical evidence on the effectiveness of COVID-19 vaccines for children aged 1–
3 years is scarce. The effectiveness of COVID-19 vaccines was evaluated among non …

[HTML][HTML] Molnupiravir for the treatment of COVID-19 outpatients: An updated meta-analysis

HA Cheema, SA Rab, M Butt, U Jafar, A Shahid… - Journal of Microbiology …, 2024 - Elsevier
Background The majority of available data on molnupiravir come from an unvaccinated
COVID-19 population. Therefore, we conducted this meta-analysis to integrate evidence …

[HTML][HTML] Exploring Paxlovid Efficacy in COVID-19 Patients with MAFLD: Insights from a Single-Center Prospective Cohort Study

M Buchynskyi, V Oksenych, I Kamyshna, O Kamyshnyi - Viruses, 2024 - mdpi.com
This study investigates the intricate interplay between Metabolic-associated Fatty Liver
Disease (MAFLD) and COVID-19, exploring the impact of MAFLD on disease severity …

COVID-19 hospitalization risk after outpatient nirmatrelvir/ritonavir use, January to August 2022, North Carolina

HI Henderson, DA Wohl, WA Fischer… - Journal of …, 2024 - academic.oup.com
Background In the USA, nirmatrelvir/ritonavir is authorized for the treatment of mild-to-
moderate COVID-19 in patients at least 12 years of age, at high risk for progression to …

[PDF][PDF] Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response

Y Wang, P Li, L Xu, AC de Vries, RJ Rottier, W Wang… - Iscience, 2023 - cell.com
Severe infections with coronaviruses are often accompanied with hyperinflammation,
requiring therapeutic strategies to simultaneously tackle the virus and inflammation. By …

Timing of BNT162b2 vaccine prior to COVID‐19 infection, influence disease severity in patients with hematologic malignancies: Results from a cohort study

O Gutwein, K Herzog Tzarfati, A Apel… - Cancer …, 2023 - Wiley Online Library
The COVID‐19 pandemic continues to pose challenges to the treatment of hemato‐
oncology patients. Emergence of COVID‐19 variants, availability of vaccine boosters and …

Combination of spironolactone and DPP-4 inhibitors for treatment of SARS-CoV-2 infection: a literature review

K Asadipooya, A Asadipooya, R Adatorwovor - Archives of Virology, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is still causing hospitalization and death,
and vaccination appears to become less effective with each emerging variant. Spike, non …

AntiViralDL: Computational Antiviral Drug Repurposing Using Graph Neural Network and Self-Supervised Learning

P Zhang, X Hu, G Li, L Deng - IEEE Journal of Biomedical and …, 2023 - ieeexplore.ieee.org
Viral infections have emerged as significant public health concerns for decades. Antiviral
drugs, specifically designed to combat these infections, have the potential to reduce the …