Impact of some antiviral drugs on health care utilization for patients with COVID-19: a systematic review and meta-analysis

B Wei, R Zhang, H Zeng, L Wu, R He… - Expert Review of Anti …, 2023 - Taylor & Francis
Background We aimed to assess the impact of antiviral drugs (fluvoxamine, remdesivir,
lopinavir/ritonavir (LPV/r), molnupiravir, andnirmatrelvir/ritonavir (NRV/r)) on health care …

[HTML][HTML] Expert consensus: main risk factors for poor prognosis in COVID-19 and the implications for targeted measures against SARS-CoV-2

FJ Candel, P Barreiro, M Salavert, A Cabello… - Viruses, 2023 - mdpi.com
The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus
type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …

[HTML][HTML] Safety and Effectiveness of Molnupiravir (LAGEVRIO®) Capsules in Japanese Patients with COVID-19: Interim Report of Post-marketing Surveillance in …

M Kimata, A Watanabe, Y Yanagida… - Infectious diseases and …, 2023 - Springer
Introduction Molnupiravir is an oral antiviral drug that received special approval for
emergency use in Japan on December 24 2021 for infectious disease caused by severe …

Risk of acute liver injury following the nirmatrelvir/ritonavir use

CKH Wong, LY Mak, ICH Au, WY Cheng… - Liver …, 2023 - Wiley Online Library
Background Elevations in alanine aminotransferase (ALT) and aspartate aminotransferase
(AST) were reported as adverse events of nirmatrelvir/ritonavir users in the EPIC‐HR trial …

Your Outpatient has Coronavirus Disease 2019: What Are the Treatment Options in the Current Severe Acute Respiratory Syndrome Coronavirus 2 Variant Climate?

WA Werbel, ED Weld, SD Advani… - Clinical Infectious …, 2023 - academic.oup.com
Mutations accumulated by novel Severe Acute Respiratory Syndrome Coronavirus 2
Omicron sublineages contribute to evasion of previously effective monoclonal antibodies for …

Effectiveness of oral antiviral agents on long‐term cardiovascular risk in nonhospitalized patients with COVID‐19: A multicenter matched cohort study

TH Liu, MH Chuang, JY Wu, PY Huang… - Journal of Medical …, 2023 - Wiley Online Library
Although a novel oral antiviral agent can improve short‐term COVID‐19 outcomes, its effects
on the long‐term outcomes, namely the risk of major adverse cardiovascular events …

[HTML][HTML] Head-to-head comparison of azvudine and nirmatrelvir/ritonavir for the hospitalized patients with COVID-19: a real-world retrospective cohort study with …

AH Wei, L Zeng, L Wang, L Gui, WT Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Nirmatrelvir/ritonavir and azvudine have been approved for the early treatment
of COVID-19 in China, however, limited real-world data exists regarding their effectiveness …

[HTML][HTML] Counterfactual analysis of the 2023 Omicron XBB wave in China

H Liu, X Xu, X Deng, Z Hu, R Sun, J Zou, J Dong… - Infectious Disease …, 2024 - Elsevier
Background China has experienced a COVID-19 wave caused by Omicron XBB variant
starting in April 2023. Our aim is to conduct a retrospective analysis exploring the dynamics …

Appraisal of evidence reliability and applicability of Paxlovid as treatment for SARS‐COV‐2 infection: A systematic review

C Zhu, JY Yin, X Chen, M Liu… - Reviews in Medical …, 2023 - Wiley Online Library
This study aimed to clarify the beneficial effect and the clinical application value of Paxlovid
in the treatment of coronavirus disease‐19 (COVID‐19) through a systematic review …

[HTML][HTML] Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal

Y Xiong, X Wang, S Li, Q Zhang, L Guo… - Frontiers in …, 2023 - frontiersin.org
Paxlovid (nirmatrelvir/ritonavir) is an antiviral drug used to treat COVID-19, nirmatrelvir, a
SARS-CoV-2 main protease inhibitor, works by inhibiting viral replication in the early stages …