The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …
M Kimata, A Watanabe, Y Yanagida… - Infectious diseases and …, 2023 - Springer
Introduction Molnupiravir is an oral antiviral drug that received special approval for emergency use in Japan on December 24 2021 for infectious disease caused by severe …
Background Elevations in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were reported as adverse events of nirmatrelvir/ritonavir users in the EPIC‐HR trial …
Mutations accumulated by novel Severe Acute Respiratory Syndrome Coronavirus 2 Omicron sublineages contribute to evasion of previously effective monoclonal antibodies for …
TH Liu, MH Chuang, JY Wu, PY Huang… - Journal of Medical …, 2023 - Wiley Online Library
Although a novel oral antiviral agent can improve short‐term COVID‐19 outcomes, its effects on the long‐term outcomes, namely the risk of major adverse cardiovascular events …
AH Wei, L Zeng, L Wang, L Gui, WT Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Nirmatrelvir/ritonavir and azvudine have been approved for the early treatment of COVID-19 in China, however, limited real-world data exists regarding their effectiveness …
H Liu, X Xu, X Deng, Z Hu, R Sun, J Zou, J Dong… - Infectious Disease …, 2024 - Elsevier
Background China has experienced a COVID-19 wave caused by Omicron XBB variant starting in April 2023. Our aim is to conduct a retrospective analysis exploring the dynamics …
C Zhu, JY Yin, X Chen, M Liu… - Reviews in Medical …, 2023 - Wiley Online Library
This study aimed to clarify the beneficial effect and the clinical application value of Paxlovid in the treatment of coronavirus disease‐19 (COVID‐19) through a systematic review …
Y Xiong, X Wang, S Li, Q Zhang, L Guo… - Frontiers in …, 2023 - frontiersin.org
Paxlovid (nirmatrelvir/ritonavir) is an antiviral drug used to treat COVID-19, nirmatrelvir, a SARS-CoV-2 main protease inhibitor, works by inhibiting viral replication in the early stages …