Context-dependent role of SIRT3 in cancer
J Zhang, J Ye, S Zhu, B Han, B Liu - Trends in Pharmacological Sciences, 2024 - cell.com
Abstract Sirtuin 3 (SIRT3), an NAD+-dependent deacetylase, plays a key role in the
modulation of metabolic reprogramming and regulation of cell death, as well as in shaping …
modulation of metabolic reprogramming and regulation of cell death, as well as in shaping …
[HTML][HTML] Sirtuins as Players in the Signal Transduction of Citrus Flavonoids
Sirtuins (SIRTs) belong to the family of nicotine adenine dinucleotide (NAD+)-dependent
class III histone deacetylases, which come into play in the regulation of epigenetic …
class III histone deacetylases, which come into play in the regulation of epigenetic …
[HTML][HTML] Structure-Function Insights into the Dual Role in Nucleobase and Nicotinamide Metabolism and a Possible Use in Cancer Gene Therapy of the URH1p …
AA Carriles, L Muzzolini, C Minici, P Tornaghi… - International Journal of …, 2024 - mdpi.com
The URH1p enzyme from the yeast Saccharomyces cerevisiae has gained significant
interest due to its role in nitrogenous base metabolism, particularly involving uracil and …
interest due to its role in nitrogenous base metabolism, particularly involving uracil and …
[HTML][HTML] Alpha Satellite DNA in Targeted Drug Therapy for Prostate Cancer
I Feliciello, Đ Ugarković - International Journal of Molecular Sciences, 2023 - mdpi.com
Prostate cancer is the most common solid cancer in men and, despite the development of
many new therapies, metastatic castration-resistant prostate cancer still remains a deadly …
many new therapies, metastatic castration-resistant prostate cancer still remains a deadly …