From bulk, single-cell to spatial RNA sequencing

X Li, CY Wang - International Journal of Oral Science, 2021 - nature.com
RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in
addition to differential gene expression, thus providing a more complete genetic picture than …

Protein-based biological materials: molecular design and artificial production

A Miserez, J Yu, P Mohammadi - Chemical Reviews, 2023 - ACS Publications
Polymeric materials produced from fossil fuels have been intimately linked to the
development of industrial activities in the 20th century and, consequently, to the …

Ensemble deep learning in bioinformatics

Y Cao, TA Geddes, JYH Yang, P Yang - Nature Machine Intelligence, 2020 - nature.com
The remarkable flexibility and adaptability of ensemble methods and deep learning models
have led to the proliferation of their application in bioinformatics research. Traditionally …

Third-generation sequencing: the spearhead towards the radical transformation of modern genomics

K Athanasopoulou, MA Boti, PG Adamopoulos… - Life, 2021 - mdpi.com
Although next-generation sequencing (NGS) technology revolutionized sequencing, offering
a tremendous sequencing capacity with groundbreaking depth and accuracy, it continues to …

Can omics deliver temperature resilient ready-to-grow crops?

A Raza, J Tabassum, H Kudapa… - Critical Reviews in …, 2021 - Taylor & Francis
Plants are extensively well-thought-out as the main source for nourishing natural life on
earth. In the natural environment, plants have to face several stresses, mainly heat stress …

Multi-omics approaches to disease

Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
High-throughput technologies have revolutionized medical research. The advent of
genotyping arrays enabled large-scale genome-wide association studies and methods for …

Database resources of the national center for biotechnology information

Nucleic acids research, 2018 - academic.oup.com
Abstract The National Center for Biotechnology Information (NCBI) provides a large suite of
online resources for biological information and data, including the GenBank® nucleic acid …

Multi-omic and multi-view clustering algorithms: review and cancer benchmark

N Rappoport, R Shamir - Nucleic acids research, 2018 - academic.oup.com
Recent high throughput experimental methods have been used to collect large biomedical
omics datasets. Clustering of single omic datasets has proven invaluable for biological and …

[HTML][HTML] Statistical methods for Mendelian randomization in genome-wide association studies: a review

FJ Boehm, X Zhou - Computational and structural biotechnology journal, 2022 - Elsevier
Genome-wide association studies have yielded thousands of associations for many
common diseases and disease-related complex traits. The identified associations made it …

A census of human RNA-binding proteins

S Gerstberger, M Hafner, T Tuschl - Nature Reviews Genetics, 2014 - nature.com
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …