Specific elements of viral genomes regulate interactions within host cells. Here, we
calculated the secondary structure content of> 2000 coronaviruses and computed> 100 000 …

T helper cell differentiation occurs in the context of the extracellular cytokine milieu evoked
by diverse microbes and other pathogenic stimuli along with T cell receptor stimulation. The …

Domestication of orphan crops could be explored by editing their genomes. Genome editing
has a lot of promise for enhancing agricultural output, and there is a lot of interest in …

The increased transmission of SARS-CoV-2 variants of concern (VOC), which originated in
the United Kingdom (B. 1.1. 7/alpha), South Africa (B1. 351/beta), Brazil (P. 1/gamma), the …

Background Skin transcriptome studies in atopic dermatitis (AD) showed broad
dysregulation as well as “improvement” under therapy. These observations were mainly …

Vegetative phase changes in plants describes the transition between juvenile and adult
phases of vegetative growth before flowering. It is one of the most fundamental mechanisms …

Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is
the alignment (mapping) of the generated reads to a reference sequence. To accomplish …

RNA sequencing is an increasingly popular technology for genome-wide analysis of
transcript sequence and abundance. However, understanding of the sources of technical …

The availability of the human genome sequence has allowed identification of disease-
causing mutations in many Mendelian disorders, and detection of significant associations of …

Solitary fibrous tumor (SFT) is a mesenchymal neoplasm displaying variable morphologic
and clinical features. To identify pathogenetically important genetic rearrangements, 44 …