[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

Overview and update on methods for cargo loading into extracellular vesicles

Y Han, TW Jones, S Dutta, Y Zhu, X Wang… - Processes, 2021 - mdpi.com
The enormous library of pharmaceutical compounds presents endless research avenues.
However, several factors limit the therapeutic potential of these drugs, such as drug …

Engineered small extracellular vesicle‑mediated NOX4 siRNA delivery for targeted therapy of cardiac hypertrophy

JY Kang, D Mun, Y Chun, DS Park… - Journal of …, 2023 - Wiley Online Library
Small‐interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for
treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and …

[HTML][HTML] The networks of noncoding RNAs and their direct molecular targets in myocardial infarction

S Wang, Y Wang, H Cheng, Q Zhang, C Fu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Noncoding RNAs are closely related to the development of myocardial infarction (MI), and
their specific roles in MI are still being carefully studied. Researchers can select the literature …

Revisiting miRNA-21 as a therapeutic strategy for myocardial infarction: a systematic review

V Sothivelr, MY Hasan, SM Saffian… - Journal of …, 2022 - journals.lww.com
Several types of cardiovascular cells use microRNA-21 (miR-21), which has been linked to
cardioprotection. In this study, we systematically reviewed the results of published papers on …

The regulation mechanisms and clinical application of microRNAs in myocardial infarction: a review of the recent 5 years

C Wu, B Liu, R Wang, G Li - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Myocardial infarction (MI) is the most frequent end-point of cardiovascular pathology,
leading to higher mortality worldwide. Due to the particularity of the heart tissue, patients …

Mechanisms of infection by SARS-CoV-2, inflammation and potential links with the microbiome

MM Aguirre Garcia, J Mancilla-Galindo… - Future …, 2021 - Taylor & Francis
The pandemic SARS coronavirus 2 utilizes efficient mechanisms to establish infection and
evade the immune system. Established infection leads to severe inflammation in susceptible …

Non-viral gene delivery systems for treatment of myocardial infarction: targeting strategies and cardiac cell modulation

J Wang, L Yu, A Zhou, J Liu, K Wang, Y Luo, F Wang - Pharmaceutics, 2021 - mdpi.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide.
Conventional therapies involving surgery or pharmacological strategies have shown limited …

Suppression of Sox4 protects against myocardial ischemic injury by reduction of cardiac apoptosis in mice

L Zhang, L Lv, N Zheng, R Li, R Yang… - Journal of Cellular …, 2021 - Wiley Online Library
Sox4 participates in the progression of embryo development and regulation of apoptosis in
tumors. However, the effect and mechanism of Sox4 in myocardial infarction (MI) remains …

[引用][C] Running Title: A Review of miR-21 for Myocardial Infarction

V Sothivelr, MY Hasan