Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells
H Song, SH Ki, SG Kim, A Moon - Cancer research, 2006 - AACR
Mounting evidence suggests a role for matrix metalloproteinase (MMP)-2 in the malignant
progression of breast cancer cells. We showed previously that H-Ras, but not N-Ras …
progression of breast cancer cells. We showed previously that H-Ras, but not N-Ras …
The host environment promotes the constitutive activation of nuclear factor-κB and proinflammatory cytokine expression during metastatic tumor progression of murine …
G Dong, Z Chen, T Kato, C Van Waes - Cancer research, 1999 - AACR
We reported previously that tumor cells isolated from metastases of the in vitro transformed
squamous cell carcinoma line Pam 212 exhibit an elevation in constitutive production of …
squamous cell carcinoma line Pam 212 exhibit an elevation in constitutive production of …
Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their …
SV Bava, CN Sreekanth, AKT Thulasidasan… - The international journal …, 2011 - Elsevier
Paclitaxel is the most promising chemotherapeutic agent of plant origin despite its high cost
and dose-limiting toxicity. Our earlier report has shown that cervical cancer cells can be …
and dose-limiting toxicity. Our earlier report has shown that cervical cancer cells can be …
Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells
DB Reardon, JN Contessa, RB Mikkelsen, K Valerie… - Oncogene, 1999 - nature.com
Exposure of MDA-MB-231 human mammary carcinoma cells to an ionizing radiation dose of
2 Gy results in immediate activation and Tyr phosphorylation of the epidermal growth factor …
2 Gy results in immediate activation and Tyr phosphorylation of the epidermal growth factor …
Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple …
G Dong, E Loukinova, Z Chen, L Gangi, TI Chanturita… - Cancer research, 2001 - AACR
To identify changes in gene expression with transformation and metastasis, we investigated
differential gene expression in a squamous carcinoma model established in syngeneic …
differential gene expression in a squamous carcinoma model established in syngeneic …
Activation of nuclear factor κB in radioresistance of TP53-inactive human keratinocytes
X Chen, B Shen, L Xia, A Khaletzkiy, D Chu, JYC Wong… - Cancer research, 2002 - AACR
Many tumors show a mutant or inactive tumor suppressor p53 (TP53) status, and TP53 in the
tumor-carrying human papillomavirus (HPV) may be dysfunctional because of inhibition by …
tumor-carrying human papillomavirus (HPV) may be dysfunctional because of inhibition by …
Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently
MR Young, R Nair, N Bucheimer, P Tulsian… - … and cellular biology, 2002 - Taylor & Francis
Mitogen-activated protein (MAP) kinase, extracellular-signal-regulated kinases (ERKs) play
an important role in activating AP-1-dependent transcription. Studies using the JB6 mouse …
an important role in activating AP-1-dependent transcription. Studies using the JB6 mouse …
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine
MC Peakman, C Colby, LI Perrotti, P Tekumalla… - Brain research, 2003 - Elsevier
Administration of cocaine induces the Fos family of transcription factors in the striatum,
including the nucleus accumbens (NAc), a brain region important for the rewarding effects of …
including the nucleus accumbens (NAc), a brain region important for the rewarding effects of …
Expression of ErbB2 enhances radiation-induced NF-κB activation
G Guo, T Wang, Q Gao, D Tamae, P Wong, T Chen… - Oncogene, 2004 - nature.com
Abstract Her-2/neu (ErbB2) oncogene, the second member of the epidermal growth factor
receptor (EGFR) family, encodes a transmembrane tyrosine kinase receptor in Her-2 …
receptor (EGFR) family, encodes a transmembrane tyrosine kinase receptor in Her-2 …
Inhibition of AP‐1 and NF‐κB by manganese‐containing superoxide dismutase in human breast cancer cells
JJ Li, LW Oberley, M Fan, NH Colburn - The FASEB journal, 1998 - Wiley Online Library
One of the primary antioxidant enzymes, manganese‐containing superoxide dismutase
(MnSOD), has shown the ability to reverse malignant phenotypes in a variety of human …
(MnSOD), has shown the ability to reverse malignant phenotypes in a variety of human …