SAG/ROC2/Rbx2 Is a Novel Activator Protein-1 Target that Promotes c-Jun Degradation and Inhibits 12-O-Tetradecanoylphorbol-13-Acetate–Induced Neoplastic …
Q Gu, M Tan, Y Sun - Cancer research, 2007 - AACR
SAG (sensitive to apoptosis gene) was first identified as a stress-responsive protein that,
when overexpressed, inhibited apoptosis both in vitro and in vivo. SAG was later found to be …
when overexpressed, inhibited apoptosis both in vitro and in vivo. SAG was later found to be …
Phase II enzyme inducer, sulforaphane, inhibits UVB‐induced AP‐1 activation in human keratinocytes by a novel mechanism
M Zhu, Y Zhang, S Cooper, E Sikorski… - … in Cooperation with …, 2004 - Wiley Online Library
Ultraviolet (UV) light‐induced activation of activator protein‐1 (AP‐1), resulting at least in
part from oxidative stress, promotes skin carcinogenesis. It has not yet been determined …
part from oxidative stress, promotes skin carcinogenesis. It has not yet been determined …
Induced expression of dominant‐negative c‐jun downregulates NFκB and AP‐1 target genes and suppresses tumor phenotype in human keratinocytes
Neoplastically transformed mouse and human keratinocytes elevate transactivation of both
activator protein 1 (AP‐1) and nuclear factor κB (NFκB) transcription factors. The present …
activator protein 1 (AP‐1) and nuclear factor κB (NFκB) transcription factors. The present …
[PDF][PDF] Antitumor activity of lantadenes in DMBA/TPA induced skin Tumors in mice: expression of transcription factors
J Kaur, M Sharma, PD Sharma, MP Bansal - Am J Biomed Sci, 2010 - researchgate.net
Various triterpenoids extracted from plants have been shown as chemopreventive agents in
cancer. Lantadene A (22β-angeoloxyloxy-3-oxoolean-12-en-28-oic acid; LA) is a …
cancer. Lantadene A (22β-angeoloxyloxy-3-oxoolean-12-en-28-oic acid; LA) is a …
AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model.
K Suzukawa, TJ Weber… - Environmental Health …, 2002 - ehp.niehs.nih.gov
The promotion-sensitive mouse epidermal JB6 cells (clone 41) have been used to identify
the tumor-promoting activity of various compounds. Because treatment by tumor promoters …
the tumor-promoting activity of various compounds. Because treatment by tumor promoters …
Deregulation of RNA polymerase III transcription in cervical epithelium in response to high-risk human papillomavirus
NL Daly, DA Arvanitis, JA Fairley, N Gomez-Roman… - Oncogene, 2005 - nature.com
RNA polymerase (pol) III transcription is a major determinant of biosynthetic capacity,
providing essential products such as tRNA and 5S rRNA. It is controlled directly by the …
providing essential products such as tRNA and 5S rRNA. It is controlled directly by the …
A novel glycosylated Cu/Zn-containing superoxide dismutase: production and potential therapeutic effect
M Angelova, P Dolashka-Angelova… - …, 2001 - microbiologyresearch.org
The fungal strain Humicola lutea 103 produces a naturally glycosylated Cu/Zn SOD. To
improve its yield, the effect of an increased concentration of dissolved oxygen (DO) on …
improve its yield, the effect of an increased concentration of dissolved oxygen (DO) on …
Nuclear matrix protein SMAR1 represses c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation
S Chakraborty, K Das, S Saha, M Mazumdar… - Journal of Biological …, 2014 - ASBMB
Matrix attachment region (MAR)-binding proteins have been implicated in the transcriptional
regulation of host as well as viral genes, but their precise role in HPV-infected cervical …
regulation of host as well as viral genes, but their precise role in HPV-infected cervical …
Bioinformatic Analyzes of the Association Between Upregulated Expression of JUN Gene via APOBEC-Induced FLG Gene Mutation and Prognosis of Cervical …
H Chen, L Zhao, J Liu, H Zhou, X Wang, X Fang… - Frontiers in …, 2022 - frontiersin.org
Globally, cervical cancer (CC) is the most common malignant tumor of the female
reproductive system and its incidence is only second after breast cancer. Although …
reproductive system and its incidence is only second after breast cancer. Although …
Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis
CP Matthews, AM Birkholz, AR Baker, CM Perella… - Cancer research, 2007 - AACR
Activation of activator protein 1 (AP-1) and nuclear factor κB (NFκB)–dependent transcription
is required for tumor promotion in cell culture models and transgenic mice. Dominant …
is required for tumor promotion in cell culture models and transgenic mice. Dominant …