Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression

MF Maritz, PJ van der Watt, N Holderness, MJ Birrer… - 2011 - degruyter.com
AP-1, a transcription factor comprised primarily of Jun and Fos family proteins, regulates
genes involved in proliferation, differentiation and oncogenesis. Previous studies …

Loss of the HPV-infection resistance EVER2 protein impairs NF-κB signaling pathways in keratinocytes

F Vuillier, G Gaud, D Guillemot, PH Commere, C Pons… - PLoS …, 2014 - journals.plos.org
Homozygous mutations in EVER genes cause epidermodysplasia verruciformis (EV),
characterized by an immune defect and the development of skin cancers associated with β …

Differential functions of Ras for malignant phenotypic conversion

A Moon - Archives of pharmacal research, 2006 - Springer
Among the effector molecules connected with the group of cell surface receptors, Ras
proteins have essential roles in transducing extracellular signals to diverse intracellular …

Effects of octreotide on epidermal growth factor receptor, tissue plasminogen activator, and plasminogen activator inhibitor during intraperitoneal adhesion formation

HS Lai, Y Chen, KJ Chang, WJ Chen - Journal of gastroenterology, 2003 - Springer
Background. Intraperitoneal adhesions remain a problem after abdominal surgery.
Octreotide has been proved to be able to reduce the number, strength, and extent of fibrous …

Proteinase inhibitors I and II from potatoes block UVB-induced AP-1 activity by regulating the AP-1 protein compositional patterns in JB6 cells

G Liu, N Chen, A Kaji, AM Bode… - Proceedings of the …, 2001 - National Acad Sciences
Proteinase inhibitor I (Inh I) and proteinase inhibitor II (Inh II) from potato tubers are effective
proteinase inhibitors of chymotrypsin and trypsin. Inh I and Inh II were shown to suppress …

Overexpression of JunB in undifferentiated malignant rat oral keratinocytes enhances the malignant phenotype in vitro without altering cellular differentiation

CM Robinson, SS Prime, S Huntley… - … journal of cancer, 2001 - Wiley Online Library
Our study examined the expression of AP‐1 family members in keratinocytes derived from
the rat‐4NQO model of oral carcinogenesis in which extremes of epithelial differentiation …

NF-κB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis

I Hussain, I Fathallah, R Accardi, J Yue, D Saidj… - Journal of …, 2011 - Am Soc Microbiol
Constitutive activation of NF-κB signaling is a key event in virus-and non-virus-induced
carcinogenesis. We have previously reported that cutaneous human papillomavirus type 38 …

Protection against human papillomavirus type 16‐E7 oncogene‐induced tumorigenesis by in vivo expression of dominant‐negative c‐jun

MR Young, L Farrell, P Lambert… - … in cooperation with …, 2002 - Wiley Online Library
Expression of the human papillomavirus (HPV) type 16 E6 and E7 gene products is a risk
factor for human cervical carcinogenesis as well as skin and oral carcinogenesis …

Role of p38 mitogen‐activated protein kinases in ultraviolet‐B irradiation–induced activator protein 1 activation in human keratinocytes

W Chen, GT Bowden - … in cooperation with the University of …, 2000 - Wiley Online Library
The effects of p38 mitogen‐activated protein kinases on ultraviolet (UV) B irradiation–
induced activator protein 1 (AP‐1) activation were studied in a human keratinocyte cell line …

Loss of cytokeratin 14 expression is related to human papillomavirus type and lesion grade in squamous intraepithelial lesions of the cervix

SA Southern, IW McDicken, CS Herrington - Human pathology, 2001 - Elsevier
In a recent study of low-grade cervical squamous intraepithelial lesions (SILs), we reported
that infection with both low-and high-risk human papillomaviruses (HPVs) upregulated cyclin …