SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Autoinflammatory and autoimmune conditions at the crossroad of COVID-19

Y Rodríguez, L Novelli, M Rojas, M De Santis… - Journal of …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has been categorized as evolving in
overlapping phases. First, there is a viral phase that may well be asymptomatic or mild in the …

Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy

A Basu, G Ramamoorthi, G Albert, C Gallen… - Frontiers in …, 2021 - frontiersin.org
Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells
in the tumor which are critical for activation of anti-tumor response either directly by …

HPV post-infection microenvironment and cervical cancer

Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions

NL Fransen, CC Hsiao, M van der Poel… - Brain, 2020 - academic.oup.com
Multiple sclerosis is a chronic inflammatory, demyelinating disease, although it has been
suggested that in the progressive late phase, inflammatory lesion activity declines. We …

Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines

R Fraser, A Orta-Resendiz, A Mazein… - Trends in molecular …, 2023 - cell.com
SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …

Origins of CD4+ circulating and tissue‐resident memory T‐cells

QP Nguyen, TZ Deng, DA Witherden… - Immunology, 2019 - Wiley Online Library
In response to infection, naive CD 4+ T‐cells proliferate and differentiate into several
possible effector subsets, including conventional T helper effector cells (TH 1, TH 2, TH 17) …

Cervical cancer heterogeneity: a constant battle against viruses and drugs

Q Sun, L Wang, C Zhang, Z Hong, Z Han - Biomarker Research, 2022 - Springer
Cervical cancer is the first identified human papillomavirus (HPV) associated cancer and the
most promising malignancy to be eliminated. However, the ever-changing virus subtypes …

[HTML][HTML] Thymus involution sets the clock of the aging T-cell landscape: Implications for declined immunity and tissue repair

Y Elyahu, A Monsonego - Ageing research reviews, 2021 - Elsevier
Aging is generally characterized as a gradual increase in tissue damage, which is
associated with senescence and chronic systemic inflammation and is evident in a variety of …

Chronic E-cigarette aerosol inhalation alters the immune state of the lungs and increases ACE2 expression, raising concern for altered response and susceptibility to …

JA Masso-Silva, A Moshensky, J Shin, J Olay… - Frontiers in …, 2021 - frontiersin.org
Conventional smoking is known to both increase susceptibility to infection and drive
inflammation within the lungs. Recently, smokers have been found to be at higher risk of …